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T2WI、DWI及Gd-EOB-DTPA增强扫描独立序列对结直肠癌肝转移瘤检出率的比较

发布时间:2018-07-21 15:16
【摘要】:目的比较T2WI、DWI及Gd-EOB-DTPA增强扫描单独序列对结直肠癌肝转移瘤的检出效能。方法选取31例结直肠癌肝转移患者,均行MR检查,包括T2WI/FS、DWI、Gd-EOB-DTPA常规动态增强(MR-Dyn)和肝细胞期(MR-Late)扫描。由2名医师共同阅片,对每组影像图像进行单独分析。记录所有检出病灶所在层面、肝段、与肝脏边缘的距离及病变大小。以手术病理、术中超声及治疗前后影像图像的综合评价作为金标准。采用配对McNemar检验比较各序列对肝转移瘤的检出率。结果 31例患者中,共检出156个肝转移瘤,大小0.3~7.3cm,≤0.5cm、0.6~1.0cm、1.1~2.0cm和2.0cm分别为20、52、50和34个。对肝转移瘤的总体检出率,T2WI/FS、DWI、MR-Dyn和MR-Late分别为84.62%(132/156)、87.18%(136/156)、67.31%(105/156)和93.59%(146/156)。MR-Late对肝转移瘤的总体检出率明显高于T2WI/FS(P=0.020)和MR-Dyn(P0.001),与DWI的差异无统计学意义(P=0.064)。对≤0.5cm肝转移瘤,T2WI/FS、DWI、MR-Dyn和MR-Late的检出率分别为30.00%(6/20)、65.00%、(13/20)25.00%(5/20)和85.00%(17/20),MR-Late检出率明显高于T2WI/FS(P=0.013)和MR-Dyn(P0.001),与DWI的差异无统计学意义(P=0.219)。对0.6~1.0cm肝转移瘤,T2WI/FS,DWI和MR-Late检出率分别为88.46%(46/52)、88.46%(46/52)和86.54%(45/52),均明显高于MR-Dyn(26/52,50.00%)。而对于1.0cm的肝转移瘤,所有序列检出率的差异均无统计学意义(P均0.05)。结论 Gd-EOB-DTPA增强扫描对结直肠癌肝转移的检出率高,尤其有助于提高≤0.5cm的肝转移瘤病灶检出率。
[Abstract]:Objective to compare the effectiveness of T 2 WI and Gd EOB DTPA enhanced sequences in detecting liver metastases from colorectal cancer. Methods 31 patients with liver metastases from colorectal cancer were examined by Mr, including T2WI / FSU Gd-EOB-DTPA (MR-Dyn) and hepatocyte phase (MR-Late). Each group of images was analyzed separately by two physicians. All detected lesions were recorded at the level, segment, distance from the edge of the liver, and size of the lesion. The gold standard was surgery and pathology, intraoperative ultrasound and image evaluation before and after treatment. The detection rate of liver metastasis was compared by paired McNemar test. Results A total of 156 hepatic metastases were detected in 31 patients with a size of 0.3 ~ 7.3 cm, 鈮,

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