斑点追踪技术评价肺动脉高压患者右心功能

发布时间：2018-07-26 06:54

【摘要】：目的探讨斑点追踪技术(STI)评价不同程度肺动脉高压(PH)患者的右心功能及其与肺动脉收缩压(PASP)的相关性。方法选取40例PH患者,根据PASP分为轻、中、重三组,轻度组(PASP 36~49 mm Hg)12例,中度组(50~70 mm Hg)13例,重度组(70 mm Hg)15例,对照组20例,利用STI技术获取右室整体纵向收缩期的峰值应变(GLS)、收缩期峰值应变率(GLSRs)、舒张早期峰值应变率(GLSRe)和舒张晚期的峰值应变率(GLSRa),同时通过经胸二维常规超声心动图获取右室舒张末横径(RVED)、右室射血分数(RVEF)、三尖瓣环收缩期位移(TAPSE)、PASP等数据,结合常规超声数据及STI结果进行对比分析。结果 TAPSE、PASP、GLS、GLSRs、GLSRe、GLSRa等指标在PH组与对照组间比较差异显著(P0.05),GLS随肺动脉压力增加呈逐渐减低趋势,在PH三组间比较差异显著(P0.05),GLSRs、GLSRe、GLSRa等指标在PH三组间无统计学差异(P0.05)。结论利用STI技术能够准确评估PH患者右心功能,为临床诊断及治疗有效性提供支持。
[Abstract]:Objective to investigate the correlation between right ventricular function and pulmonary systolic pressure (PASP) in patients with pulmonary hypertension (PH) by speckle tracing technique (STI). Methods 40 patients with PH were divided into three groups according to PASP: mild group (PASP 3649 mm Hg), n = 12), moderate group (n = 13), severe group (n = 15, n = 15) and control group (n = 20). Peak strain of right Ventricular whole Vertical systolic period (GLS), peak strain rate (GLSRs), early diastolic peak strain rate (GLSRe) and late diastolic peak strain rate (GLSRa), obtained by transthoracic conventional echocardiography Right ventricular end-diastolic diameter (RVED), right ventricular ejection fraction (RVEF), tricuspid annular systolic displacement (TAPSE), etc. The results of conventional ultrasound and STI were compared and analyzed. Results there was a significant difference between the PH group and the control group (P0.05). The GLS gradually decreased with the increase of pulmonary artery pressure, but there was no significant difference among the three PH groups (P0.05). Conclusion STI can accurately evaluate the right ventricular function in patients with PH, and provide support for clinical diagnosis and treatment.
【作者单位】：吉林大学第一医院心血管中心超声室;吉林大学第一医院检验科;
【基金】：吉林省发改委计划项目(No.2015Y034-4)
【分类号】：R445.1;R544.1

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