超声造影鉴别诊断乳腺良恶性肿瘤

发布时间：2018-07-27 14:19

【摘要】：目的探讨超声造影(CEUS)鉴别诊断乳腺良恶性肿瘤的应用价值。方法纳入277例乳腺肿瘤患者,均行常规超声(BUS)及CEUS检查,并与病理结果进行对照,对BUS及CEUS各观察指标进行Logistic回归分析,比较BUS与CEUS鉴别诊断乳腺良恶性肿瘤的效能。结果 277例患者中,良性病变184例(良性组),恶性病变93例(恶性组)。Logistic回归分析显示,BUS诊断恶性肿瘤的危险指标为中等血供、非平行生长、血供丰富及边界模糊,相对危险度分别为5.17、4.84、3.39、3.04;CEUS为离心性增强、向心性增强、肿瘤形状不规则、造影剂分布不均、增强后范围增大,相对危险度分别为13.36、4.58、4.07、3.28、2.36。BUS诊断乳腺肿瘤的准确率为81.59%(226/277),CEUS为88.09%(244/277),二者差异有统计学意义(χ2=1.012,P0.001)。结论采用CEUS鉴别诊断乳腺良恶性肿瘤的准确率较高,其在乳腺局灶性病变的定性诊断中具有一定的应用价值。
[Abstract]:Objective to evaluate the value of contrast-enhanced (CEUS) in differential diagnosis of breast benign and malignant tumors. Methods (BUS) and CEUS were performed in 277 patients with breast neoplasms, and compared with pathological results, Logistic regression analysis was performed on BUS and CEUS. The effectiveness of BUS and CEUS in differential diagnosis of benign and malignant breast tumors was compared. Results among 277 patients, 184 cases were benign lesions (benign group), 93 cases were malignant lesions (malignant group) .Logistic regression analysis showed that the risk index for diagnosis of malignant tumor was medium blood supply, non-parallel growth, abundant blood supply and fuzzy boundary. The relative risk was 5.17 ~ 4.84 ~ 3.39 ~ 3.04 CEUs for centrifugal enhancement, concentric enhancement, irregular shape of tumor, uneven distribution of contrast media, and increased range after enhancement. The relative risk was 13.36 / 4.587 / 3.28 / 2.36. Bus was 81.59% (226 / 277) and CEUS was 88.09% (244 / 277), respectively. The difference was statistically significant (蠂 ~ 2 ~ (2) n ~ (1) 12) (P ~ (0.001). Conclusion the accuracy of CEUS in differential diagnosis of breast benign and malignant tumors is high, and it has certain application value in qualitative diagnosis of local breast lesions.
【作者单位】：中山大学附属第一医院超声科;
【基金】：广东省省级科技计划项目(2013B021800291)
【分类号】：R445.1;R737.9

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