囊腔冲洗技术在甲状腺胶质囊肿无水乙醇硬化治疗中的应用

发布时间：2018-08-04 14:08

【摘要】：目的探讨囊腔冲洗技术在甲状腺胶质囊肿无水乙醇硬化治疗中的应用价值。方法 49例甲状腺胶质囊肿随机分配入研究组(33例)和对照组(16例)进行治疗,研究组以0.9%氯化钠溶液混合α-糜蛋白酶冲洗囊腔后行无水乙醇硬化治疗,对照组则单纯抽吸囊液后行无水乙醇硬化治疗。术后1、3、6个月比较两组残存囊腔体积变化、治疗有效率及不良反应情况。结果治疗后残存囊腔体积变化研究组与对照组差别明显,治疗有效率研究组(93.9%)优于对照组(68.8%),差异均有统计学意义(P0.05);研究组与对照组囊液抽吸冲洗过程均无不良反应发生,两组不良反应均出现在乙醇硬化治疗过程中(6.1%比8.3%),差异无统计学意义(P=0.75)。结论 0.9%氯化钠溶液混合α-糜蛋白酶囊腔冲洗技术应用于甲状腺胶质囊肿黏稠囊液冲洗抽吸是一种安全可靠的方法 ,能提高无水乙醇硬化治疗的效果。
[Abstract]:Objective to evaluate the value of cavity irrigation in the treatment of thyroid glial cyst with anhydrous ethanol. Methods Forty-nine cases of thyroid glial cysts were randomly assigned to the study group (33 cases) and the control group (16 cases). The study group was treated with 伪 -chymotrypsin in 0.9% sodium chloride solution after washing the capsule cavity with anhydrous ethanol sclerosis. The control group was treated with anhydrous ethanol sclerotherapy. The changes of residual cavity volume, effective rate and adverse reaction were compared between the two groups at 1: 3 and 6 months postoperatively. Results the change of residual cavity volume in the study group was significantly different from that in the control group, the effective rate of treatment in the study group (93.9%) was better than that in the control group (68.8%), the difference was statistically significant (P0.05), there was no adverse reaction in the process of aspiration and washing of the sac fluid in the study group and the control group. The adverse reactions of the two groups occurred during the treatment of ethanol sclerosis (6.1% vs 8.3%), but there was no significant difference (P0. 75). Conclusion the application of 0.9% sodium chloride solution mixed with 伪 -chymotrypsin in washing and aspiration of goitre glial cysts is a safe and reliable method, which can improve the effect of anhydrous ethanol sclerotherapy.
【作者单位】：湖州市中心医院超声科;
【基金】：浙江省湖州市科技计划项目(2016GYB34)
【分类号】：R445.1;R581

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