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早期乳腺癌术后大分割放射治疗50例临床分析

发布时间:2018-08-07 13:53
【摘要】:目的探讨早期乳腺癌保乳术后乳腺大分割放射治疗的毒性、美容效果及相关风险因素。方法 50例患者早期乳腺癌保乳术后实行大分割放射治疗,放射治疗量:42.50 Gy/16 F 3.2周,2.66 Gy/F,局部瘤床加量9.00 Gy/3 F,在放射治疗过程中及放射治疗后对急性及迟发性的毒性反应及美容效果进行评估。结果中位数随访36个月,8例患者无急性反应(16%),发生Ⅰ级急性皮肤毒性反应33例(66%),Ⅱ级急性皮肤毒性反应9例(18%)。发生Ⅰ级晚期皮肤毒性反应10例(20%),Ⅱ级晚期皮肤毒性反应1例(2%)。主观和客观上判定放射治疗后乳房美容效果优良率分别为94%和93%。结论早期乳腺癌保乳术后乳腺大分割放射治疗是可行和安全的,急性及晚期毒性反应可以接受。
[Abstract]:Objective to investigate the toxicity, cosmetic effect and risk factors of mammary hypersegmentation radiotherapy after breast conserving surgery for early breast cancer. Methods 50 patients with early breast cancer were treated with massive fractionation radiotherapy after breast conserving surgery. The dose of radiation was 42.50 Gy/16 / F 3.2 weeks or 2.66 Gy / F, and the local tumor bed dosage was 9.00 Gy/3 / F. The acute and delayed toxic reactions and cosmetic effects were evaluated during and after radiotherapy. Results there were no acute reaction (16%), 33 cases (66%) had acute dermatotoxicity in grade 鈪,

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