四维左心室容积定量分析工具评价二维超声心动图目测无室壁运动异常冠心病患者左室功能
发布时间：2018-08-11 20:36
【摘要】：目的：探讨四维左心室容积定量分析工具(4DLVQ)评价常规二维超声心动图目测无室壁运动异常冠心病患者左室心肌功能的价值。 方法：62例常规二维超声心动图目测无室壁运动异常但经冠脉造影证实冠心病患者(冠心病组)、48例健康志愿者(对照组)。分别应用二维双平面改良Simpson法测量左室舒张末期容积、收缩末期容积及射血分数(2D-LVEF),实时三平面自动化功能成像(AFI)测量左室长轴整体径向峰值应变(GLPS),4DLVQ测量四维左室舒张末期容积、收缩末期容积、左室射血分数(4D-LVEF)及左室收缩末期整体纵向应变(GLS)、圆周应变(GCS)、面积应变(GAS)、径向应变(GRS)。 结果：1、冠心病组4D-LVEDV较对照组增大(P0.01),4D-LVEF、GLPS、 GLS、GCS、GAS、GRS均低于对照组(P0.01)； 2、冠心病组的4D-LVEF与GLPS、GLS、GCS、GAS、GRS有良好相关性,与GAS的相关性最高(r=-0.831), GCS、GLS、GRS次之(r=-0.815；r=-0.758; r=0.708),与AFI测量的GLPS相关性最低(r=-0.705); 3,4DLVQ测量的4D-LVEDV、4D-LVESV、4D-LVEF、GLS、GCS、GAS、 GRS均有较好的重复性。 结论：4DLVQ测定左室射血分数及收缩末期心肌应变能敏感、准确地评价常规二维超声心动图目测无室壁运动异常冠心病患者左室心肌功能变化,四维应变中尤以面积应变最佳。
[Abstract]:Objective: to evaluate the value of four dimensional quantitative analysis of left ventricular volume (4DLVQ) in evaluating left ventricular myocardial function in patients with coronary heart disease without ventricular wall motion abnormality by conventional two-dimensional echocardiography. Methods Sixty-two cases of coronary heart disease (CHD group) with coronary artery disease (CHD) confirmed by coronary angiography (CHD group) were examined by routine two-dimensional echocardiography in 48 healthy volunteers (control group). The left ventricular end-diastolic volume, end-systolic volume and ejection fraction (2D-LVEF) were measured by two-dimensional biplane modified Simpson method, respectively. The left ventricular end-diastolic volume was measured by real-time three-plane automatic functional imaging (AFI). The global radial peak strain of left ventricular long axis was measured by (GLPS) 4DLVQ, and the left ventricular end-diastolic volume was measured by four-dimensional left ventricular end-diastolic volume (4DLVQ). End systolic volume, left ventricular ejection fraction (4D-LVEF) and left ventricular end systolic global longitudinal strain (GLS), circumferential strain (GCS), area strain (GAS), radial strain (GRS). Results the 4D-LVEDV of the coronary heart disease group was significantly higher than that of the control group (P0.01), and the GRS of the GAS-GAS-GASS of the coronary heart disease group was lower than that of the control group (P0.01), while the 4D-LVEF of the coronary heart disease group had a good correlation with the GLPS-GLSS-GAS-GAS-GRS, the highest correlation was with the GAS (r-0.831), the second was the GLSS-GRS (r-0.815). The correlation with GLPS measured by AFI was the lowest (r-0.705), and 4D-LVEDVV with 4D-LVESVV (4D-LVEF / GLSS-GCSGAS-GAS-GRS) by 3DLVQ was better than that measured by AFI (r = 0.758; r = 0.708, r = -0.758, r = 0.708, r = -0.758). Conclusion the measurement of left ventricular ejection fraction (LVEF) and end-systolic myocardial strain by W4DLVQ is sensitive. Conventional two-dimensional echocardiography can accurately evaluate the changes of left ventricular myocardial function in patients with coronary heart disease without abnormal ventricular wall motion. The area strain is the best in four-dimensional strain.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R541.4;R540.45
本文编号：2178169
[Abstract]:Objective: to evaluate the value of four dimensional quantitative analysis of left ventricular volume (4DLVQ) in evaluating left ventricular myocardial function in patients with coronary heart disease without ventricular wall motion abnormality by conventional two-dimensional echocardiography. Methods Sixty-two cases of coronary heart disease (CHD group) with coronary artery disease (CHD) confirmed by coronary angiography (CHD group) were examined by routine two-dimensional echocardiography in 48 healthy volunteers (control group). The left ventricular end-diastolic volume, end-systolic volume and ejection fraction (2D-LVEF) were measured by two-dimensional biplane modified Simpson method, respectively. The left ventricular end-diastolic volume was measured by real-time three-plane automatic functional imaging (AFI). The global radial peak strain of left ventricular long axis was measured by (GLPS) 4DLVQ, and the left ventricular end-diastolic volume was measured by four-dimensional left ventricular end-diastolic volume (4DLVQ). End systolic volume, left ventricular ejection fraction (4D-LVEF) and left ventricular end systolic global longitudinal strain (GLS), circumferential strain (GCS), area strain (GAS), radial strain (GRS). Results the 4D-LVEDV of the coronary heart disease group was significantly higher than that of the control group (P0.01), and the GRS of the GAS-GAS-GASS of the coronary heart disease group was lower than that of the control group (P0.01), while the 4D-LVEF of the coronary heart disease group had a good correlation with the GLPS-GLSS-GAS-GAS-GRS, the highest correlation was with the GAS (r-0.831), the second was the GLSS-GRS (r-0.815). The correlation with GLPS measured by AFI was the lowest (r-0.705), and 4D-LVEDVV with 4D-LVESVV (4D-LVEF / GLSS-GCSGAS-GAS-GRS) by 3DLVQ was better than that measured by AFI (r = 0.758; r = 0.708, r = -0.758, r = 0.708, r = -0.758). Conclusion the measurement of left ventricular ejection fraction (LVEF) and end-systolic myocardial strain by W4DLVQ is sensitive. Conventional two-dimensional echocardiography can accurately evaluate the changes of left ventricular myocardial function in patients with coronary heart disease without abnormal ventricular wall motion. The area strain is the best in four-dimensional strain.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R541.4;R540.45
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，本文编号：2178169
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