彩色多普勒超声对儿童糖尿病肾动脉血流动力学变化的研究

发布时间：2018-08-18 19:58

【摘要】：目的通过研究1型糖尿病儿童肾叶间动脉血流动力学指标参数的变化,探讨彩色多普勒超声检查对糖尿病肾病潜伏期的临床应用价值。资料与方法选取1型糖尿病儿童52例及健康对照组51例进行肾脏彩色多普勒超声检查,测量肾叶间动脉的阻力指数(RI),并对其临床资料及实验室指标进行比较。结果糖尿病组左肾RI、右肾RI及双肾平均RI均较对照组明显增高,差异有统计学意义(P0.01)。糖尿病组平均RI与糖化血红蛋白呈正相关(r=0.96,P0.01),与糖尿病持续时间亦呈正相关(r=0.31,P0.01)。糖尿病组空腹血糖、糖化血红蛋白、肾小球滤过率均明显高于对照组,差异有统计学意义(P0.01)。结论 1型糖尿病患儿肾叶间动脉RI指数增高,彩色多普勒超声检查能提示肾脏血流动力学改变情况,对早期糖尿病肾病诊断具有一定的价值。
[Abstract]:Objective to study the changes of hemodynamic parameters of renal interlobar artery in children with type 1 diabetes mellitus and to explore the clinical application value of color Doppler ultrasonography in the latent period of diabetic nephropathy. Materials and methods 52 children with type 1 diabetes mellitus and 51 healthy controls were examined by color Doppler ultrasonography. The resistance index (RI),) of interlobar renal artery was measured and the clinical data and laboratory indexes were compared. Results the RI of left kidney, RI of right kidney and average RI of both kidneys in diabetic group were significantly higher than those in control group (P0.01). The mean RI in diabetic group was positively correlated with glycosylated hemoglobin (r = 0.96, P 0.01), and with the duration of diabetes (r = 0.31, P 0.01). Fasting blood glucose, glycosylated hemoglobin and glomerular filtration rate in diabetic group were significantly higher than those in control group (P0.01). Conclusion RI index of renal interlobar artery is increased in type 1 diabetic children. Color Doppler ultrasound can indicate the change of renal hemodynamics and has certain value in the diagnosis of early diabetic nephropathy.
【作者单位】：广州市妇女儿童医疗中心超声科;
【分类号】：R445.1;R725.8

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