3.0T磁共振single shot PSIR与segmented PSIR序列在心肌梗死评价中的对比研究

发布时间：2018-08-22 14:19

【摘要】：目的探讨单次屏气单次激发相位重聚梯度回波相位对比反转恢复序列(single shot true-FISPPSIR)与多次屏气k空间节段填充快速扰相梯度回波相位对比反转恢复序列(segmented-turbo-FLASH-PSIR)在心脏磁共振增强扫描(CE-CMR)中定性及定量评价心肌梗死的比较优势。方法纳入临床诊断心肌梗死并行心脏磁共振增强检查的患者38例,按标准扫描方案,在完成心肌首过灌注(钆对比剂,0.15mmol/kg)12~20min后行心肌延迟扫描。分别采用single shot true-FISP-PSIR和segmented-turbo-FLASH-PSIR两种延迟扫描方案完成左心室短轴扫描。比较两种序列图像的质量,并采用心脏磁共振图像分析软件(Q-mass,Medis)自动测量每位患者的梗死心肌体积和梗死心肌比例(ratio),比较两种不同序列对于定量评价梗死心肌体积和比例的差异。结果所有患者均成功完成所有扫描。两种序列采集的心肌延迟强化图像对比度噪声比差异无统计学意义(P0.05);两种序列间左室心肌总体积差异无统计学意义(P0.05),同时single shot true-FISP-PSIR梗死心肌体积〔(30.87±15.72)mL〕及梗死心肌比例(22.94%±10.94%)与segmented-turbo-FLASH-PSIR相比〔(29.26±14.07)mL,(20.75%±8.78%)〕,差异无统计学意义(P0.05);但前者平均采集时间(20.4s)短于后者(380s)。结论Single shot true-FISP-PSIR心脏磁共振延迟扫描技术能够实现单次屏气的准确的心肌梗死范围的定量评价,与常规segmented-turbo-FLASH-PSIR序列效果相当,并能显著缩短扫描时间,值得在临床和研究中应用。
[Abstract]:Objective to investigate the effects of phase contrast inversion recovery sequence (single shot true-FISPPSIR) and phase contrast inversion recovery sequence (segmented-turbo-FLASH-PSIR) on phase contrast gradient echo (segmented-turbo-FLASH-PSIR) of single breath-holding phase reentrant gradient echo (segmented-turbo-FLASH-PSIR) in cardiac magnetic resonance imaging (Mr). Quantitative and qualitative evaluation of myocardial infarction in contrast enhanced scanning (CE-CMR). Methods Thirty-eight patients with myocardial infarction and cardiac magnetic resonance enhanced examination were included. According to the standard scan scheme, myocardial delayed scanning was performed after completion of myocardial first-pass perfusion (gadolinium contrast agent 0.15 mmol / kg) 12~20min. Left ventricular short-axis scanning was performed by single shot true-FISP-PSIR and segmented-turbo-FLASH-PSIR. The quality of the two sequences was compared, and the volume and ratio of infarcted myocardium were measured automatically by using Q-mass-Medis software. The difference of the volume and proportion of infarcted myocardium was compared between the two sequences in quantitative evaluation of infarct myocardial volume and ratio. Results all the patients completed all the scans successfully. There was no significant difference in contrast noise ratio between the two sequences (P0.05), but there was no significant difference in the total left ventricular volume between the two sequences (P0.05), while the infarcted myocardial volume of single shot true-FISP-PSIR was (30.87 卤15.72) mL) and that of the infarcted myocardium was (30.87 卤15.72) mL). Ratio (22.94% 卤10.94%) compared with segmented-turbo-FLASH-PSIR (29.26 卤14.07) mL, (20.75% 卤8.78%),) The difference was not statistically significant (P0.05), but the average acquisition time of the former (20.4s) was shorter than that of the latter (380s). Conclusion Single shot true-FISP-PSIR cardiac magnetic resonance delayed scanning technique can achieve accurate quantitative evaluation of myocardial infarction size with single breath-holding, which is comparable to that of conventional segmented-turbo-FLASH-PSIR sequence, and can significantly shorten the scanning time. It is worthy of clinical application and research.
【作者单位】：四川大学华西医院放射科;四川大学华西医院心内科;中国科学院深圳先进技术研究院;
【基金】：国家自然科学基金(No.81271531)资助
【分类号】：R445.2;R542.22

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