常规超声与声触诊组织量化技术鉴别诊断甲状腺结节的对比研究

发布时间：2018-08-28 14:07

【摘要】：目的探讨常规超声与声触诊组织量化技术(VTQ)鉴别诊断甲状腺良、恶性结节的价值。方法选取2012年2月—2014年10月在石河子大学医学院第一附属医院就诊以甲状腺结节(长径1 cm)收入院患者94例,均进行常规超声及VTQ检查,并行甲状腺切除术,经病理确诊。常规超声采用半定量评分法;VTQ定量测定结节内剪切波速度(SWV),利用受试者工作特征(ROC)曲线比较常规超声与VTQ诊断甲状腺恶性结节的效能。结果以病理检查为金标准,常规超声诊断甲状腺恶性结节的灵敏度、特异度、正确率分别为80.4%(41/51)、81.4%(35/43)、80.9%(76/94)。甲状腺恶性结节SWV高于甲状腺良性结节〔(3.29±1.20)m/s与(1.98±0.45)m/s〕(t=-6.813,P0.001)。以SWV=2.75 m/s为截断值,VTQ诊断甲状腺恶性结节的灵敏度、特异度、正确率分别为92.2%(47/51)、88.4%(38/43)、90.4%(85/94)。常规超声与VTQ诊断甲状腺恶性结节的ROC曲线下面积分别为0.804、0.918,差异有统计学意义(Z=5.576,P0.001)。结论常规超声与VTQ均有助于鉴别诊断甲状腺良、恶性结节,VTQ明显优于常规超声。
[Abstract]:Objective to evaluate the value of (VTQ) in the differential diagnosis of benign and malignant thyroid nodules by conventional ultrasound and acoustic palpation. Methods from February 2012 to October 2014, 94 patients with thyroid nodules (long diameter 1 cm) were enrolled in the first affiliated Hospital of Shihezi University Medical College. All patients were examined by conventional ultrasound and VTQ, followed by thyroidectomy, which was confirmed by pathology. (SWV), was used to measure the shear wave velocity in nodules by using semi-quantitative scoring method. The diagnostic efficacy of conventional ultrasound and VTQ in diagnosing thyroid malignant nodules was compared with that of conventional ultrasound and VTQ using the operating characteristic (ROC) curve of the subjects. Results the sensitivity, specificity and accuracy of conventional ultrasound in the diagnosis of malignant thyroid nodules were 80.4% (41 / 51) and 81.4% (35 / 43), respectively. The SWV of malignant thyroid nodules was higher than that of benign thyroid nodules (3.29 卤1.20) m / s and (1.98 卤0.45) m / s (t ~ (-6.813) P ~ (0.001). The sensitivity, specificity and accuracy of VTQ for diagnosis of malignant thyroid nodules were 92.2% (47 / 51) or 88.4% (38 / 43) or 90.4% (85 / 94), respectively. The area under the ROC curve of conventional ultrasound and VTQ were 0.804 ~ 0.918, respectively, and the difference was statistically significant (P 0.001). Conclusion both conventional ultrasound and VTQ are helpful in differential diagnosis of benign thyroid gland and malignant nodule VTQ is superior to conventional ultrasound.
【作者单位】：石河子大学医学院第一附属医院功能科;
【分类号】：R445.1;R581.3

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