相位对比磁共振成像对脑积水诊疗的作用

发布时间：2018-09-02 07:42

【摘要】：目的探讨相位对比磁共振成像(PC-MRI)技术在诊断脑积水(梗阻性、交通性脑积水)病变的应用价值和对内镜下第三脑室底造瘘术(ETV)疗效的评估。方法采用Phillips 3.0 T PC-MRI设备,测量15例正常志愿者(正常对照组)、9例梗阻性脑积水(梗阻性积水组)、11例交通性脑积水(交通性脑积水组)、6例内镜下ETV患者(ETV术后组)的中脑导水管脑脊液(CSF)动力学指标(收缩期峰值流速、舒张期峰值流速、搏出量),分别对4组的各项指标采用SNK-q检验进行组间两两比较。结果 (1)正常对照组、交通性脑积水组和ETV术后组的中脑导水管水平CSF运动呈双向、正弦曲线曲线,交通性性脑积水组的峰值流速较高且收缩期峰值流速高于舒张期。(2)正常对照组、梗阻性脑积水、交通性脑积水及ETV术后4组间峰值流速及搏出量两两比较其差异均有统计学意义(均P0.05)。结论 PC-MRI可用作特定位置流速及流量的定量分析,用来鉴别诊断脑积水的类型,对ETV术后疗效有明确的判断作用。
[Abstract]:Objective to evaluate the application of phase contrast magnetic resonance imaging (PC-MRI) in the diagnosis of hydrocephalus (obstructive, communicating hydrocephalus) and to evaluate the efficacy of (ETV) in endoscopic third ventriculostomy. Methods Phillips 3.0T PC-MRI equipment was used. The (CSF) motility of cerebrospinal fluid of midbrain aqueduct in 15 normal volunteers (normal control group), 9 obstructive hydrocephalus (obstructive hydrocephalus group), 11 communicating hydrocephalus (communicating hydrocephalus group) and 6 endoscopic ETV patients (ETV postoperative group) were measured. Mechanical parameters (peak systolic velocity, Peak diastolic velocity and stroke volume were compared with each other by SNK-q test. Results (1) the CSF movement of the midbrain aqueduct in the normal control group, the communicating hydrocephalus group and the ETV postoperative group was bidirectional and sinusoidal. The peak flow velocity and systolic peak velocity in communicating hydrocephalus group were higher than that in diastolic phase. (2) in normal control group, obstructive hydrocephalus, obstructive hydrocephalus, There were significant differences in peak velocity and stroke volume between the four groups after ETV and communicating hydrocephalus (P0.05). Conclusion PC-MRI can be used for quantitative analysis of flow rate and flow rate in specific locations, and can be used to differentiate the types of hydrocephalus, which can be used to judge the curative effect of ETV.
【作者单位】：吉林大学中日联谊医院放射线科;
【基金】：国家自然科学基金青年科学基金项目(No.81501459) 吉林省教育厅十三五科学技术研究项目(No.吉教科合字(2016)第467号)
【分类号】：R445.2;R742.7

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