基于超声造影图像的肝结节WSTT参数成像初步研究

发布时间：2018-09-04 17:42

【摘要】：目的分析不同类型局灶性肝结节(FLLs)的过渡时间加权和(WSTT)参数成像特点,初步探讨该参数在超声造影定量分析中的应用潜力。方法利用时间-强度曲线的上升支和下降支过渡时间构建一个加权参数WSTT。其中,权重参数参照时间-强度曲线峰值设置。采用36个不同类型FLLs的超声造影病例来评价WSTT参数成像的有效性。上升支和下降支的相关权重参数值分别为0.7和0.2。实验分析不同类型FLLs的WSTT参数成像特点并计算每个病例中肝结节与肝实质的WSTT比值。结果每种类型FLL的WSTT参数图能明显反映不同血流灌注特点。以肝局部脂肪缺失作为正常对照组,其他类型的FLLs的WSTT比值与对照组有明显差异(P0.05)。结论本实验初步验证了WSTT参数用于FLLs的鉴别诊断的可行性。
[Abstract]:Objective to analyze the characteristics of transitional time weighting and (WSTT) parameter imaging of different types of focal hepatic nodules (FLLs), and to explore the potential application of these parameters in quantitative analysis of contrast-enhanced ultrasound (CEUs). Methods using the transition time of ascending and descending branches of time-intensity curve to construct a weighted parameter WSTT. Among them, the weight parameter reference time-strength curve peak setting. The validity of WSTT parameter imaging was evaluated by 36 cases of different types of FLLs contrast-enhanced ultrasound. The relative weights of ascending branch and descending branch were 0.7 and 0.2 respectively. The characteristics of WSTT parameters of different types of FLLs were analyzed and the WSTT ratio of hepatic nodules to hepatic parenchyma was calculated in each case. Results the WSTT parameters of each type of FLL could reflect the characteristics of blood perfusion. The WSTT ratio of other types of FLLs was significantly different from that of the control group (P0.05). Conclusion the feasibility of using WSTT parameters in differential diagnosis of FLLs was preliminarily verified.
【作者单位】：广州军区武汉总医院医学工程科;天津医科大学肿瘤医院超声科;天津医科大学生物医学工程学院;
【基金】：国家自然科学基金(No.81272495) 国家青年科学基金(No.81401474) 广州军区武汉总医院院内课题(No.YZ201424)
【分类号】：R445.1;R575

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