动态对比增强MR定量分析在布氏杆菌性脊柱炎、脊柱结核和脊柱转移瘤鉴别诊断中的价值
发布时间：2018-09-05 20:52
【摘要】：目的应用动态对比增强(DCE)-MRI对布氏杆菌性脊柱炎、脊柱结核、脊柱转移瘤进行定量分析,评估定量DCE-MRI在上述疾病鉴别诊断中的价值。方法收集有完整生化检验或手术资料的布氏杆菌性脊柱炎患者30例,男性19例,女性11例,平均年龄50岁;脊柱结核患者30例,男性20例,女性10例,平均年龄44岁;脊柱转移瘤患者30例,男性16例,女性14例,平均年龄60岁。所有患者均行常规MRI及DCE-MRI检查,在灌注参数图上测量上述疾病患者病变椎体的容积转运常数(K~(trans))、速率常数(K_(ep))、血管外细胞外容积分数(V_e)、血浆容积分数(V_p)值。各指标均呈非正态分布,以中位数(M)±四分位数间距(Q)表示,3种病变各指标的比较均采用秩和检验。结果在布氏杆菌性脊柱炎、脊柱结核、脊柱转移瘤病变椎体中,K~(trans)值分别为(0.716±0.017)、(0.316±0.004)、(0.986±0.012)min~(-1),K_(ep)值分别为(1.326±0.018)、(0.747±0.005)、(2.899±0.054)min~(-1),V_e值分别为0.541±0.011、0.427±0.017、0.338±0.007,V_p值分别为0.034±0.003、0.029±0.003、0.049±0.007,3种病变间差异均有统计学意义(H值分别为50.24、52.49、48.31、46.54,P值均0.01)。结论DCE-MRI定量分析在布氏杆菌性脊柱炎、脊柱结核、脊柱转移瘤鉴别诊断中具有一定价值。
[Abstract]:Objective to evaluate the value of quantitative DCE-MRI in differential diagnosis of brucellosis spondylitis, spinal tuberculosis and spinal metastases by dynamic contrast enhanced (DCE). Methods A total of 30 patients with brucellosis were collected, including 19 males and 11 females, with an average age of 50 years, and 30 patients with spinal tuberculosis, 20 males and 10 females, with an average age of 44 years. There were 30 patients with spinal metastases, 16 males and 14 females with an average age of 60 years. All the patients were examined by routine MRI and DCE-MRI. The volume transport constant (K ~ (trans), rate constant) (K _ (ep), extracellular volume fraction (ve) and plasma volume fraction (VP) were measured on perfusion parameter map. The mean (M) 卤quartile interval (Q) was used to show that all the indexes were nonnormal, and the rank sum test was used to compare each index of the three lesions in terms of median (M) 卤quartile spacing. 缁撴灉鍦ㄥ竷姘忔潌鑿屾，
本文编号：2225431
[Abstract]:Objective to evaluate the value of quantitative DCE-MRI in differential diagnosis of brucellosis spondylitis, spinal tuberculosis and spinal metastases by dynamic contrast enhanced (DCE). Methods A total of 30 patients with brucellosis were collected, including 19 males and 11 females, with an average age of 50 years, and 30 patients with spinal tuberculosis, 20 males and 10 females, with an average age of 44 years. There were 30 patients with spinal metastases, 16 males and 14 females with an average age of 60 years. All the patients were examined by routine MRI and DCE-MRI. The volume transport constant (K ~ (trans), rate constant) (K _ (ep), extracellular volume fraction (ve) and plasma volume fraction (VP) were measured on perfusion parameter map. The mean (M) 卤quartile interval (Q) was used to show that all the indexes were nonnormal, and the rank sum test was used to compare each index of the three lesions in terms of median (M) 卤quartile spacing. 缁撴灉鍦ㄥ竷姘忔潌鑿屾，
本文编号：2225431
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