实时组织弹性成像中超声探头压力反馈控制的实验研究
发布时间：2018-09-10 06:35
【摘要】：目的探讨定量反馈控制实时组织弹性成像(RTE)检查过程中探头施加的压力区间与压放频率对应变比值(SR)测量重复性和准确性的影响。方法在日立HI VISION preirus型超声诊断仪,EUP-L74M浅表超声探头两侧分别加装一个FS01型压力传感器,构成压力反馈式超声弹性成像探头(以下简称压力探头),通过图像采集卡和数据采集卡将弹性图像和探头施予组织的“轻压-解压”的压力区间和压放频率实时传输到笔记本电脑操作面板上便于及时调控和观察,通过该系统可以实时调整探头压力区间及压放频率以获得满意的弹性成像图。实验分别对压力探头做重复性及准确性检验,方法如下:(1)重复性实验:15位不同熟练度的操作者分别对杨氏模量为80 kPa、直径为10.4 mm、中心深度为3 cm的超声圆柱形仿体进行3组不同条件下的RTE检查:组1为参考压放推荐指标2-3的常规方法;组2在0~80 g的压力区间、1.5次/s的压放频率引导下进行弹性成像检查;组3在40~120 g的压力区间、1.5次/s的压放频率的引导下进行检查,每组条件下均对满意的弹性成像图进行SR值测量,每位医师每组条件下均测量15次SR值,计算每位医师各组SR测量值的CV值,并分析组与组之间CV值有无明显差异。(2)准确性实验:分别在使用仪器自带的压放推荐指标2-3(对照组)和在0~100g压力区间、1.5次/s压放频率的引导条件下(实验组)测量弹性模量为(8,14,45和80kPa),直径10.4 mm,中心深度3cm的4处圆柱形超声仿体的应变比值(SR),两组条件下每个硬度仿体各测量45次,并将每组条件下测量数据分为3组,计算并比较组Ⅰ(80 kPa vs 45,14,8 kPa),组Ⅱ(80,45 kPa vs 14,8 kPa)和组Ⅲ(80,45,14kPa vs 8 kPa)的两组实验条件下的ROC曲线下面积(AUC),以及两组条件下测得4种弹性模量仿体的SR值有无差异。结果(1)重复性实验:3组条件下15位操作医师的CV值比较,差异有统计学意义(F=15.853,P0.001),组2与组3的CV值均低于组1的CV值,差异均有统计学意义(q=4.732,P0.001;q=5.038,P0.001),组2与组3的CV值比较,无统计学差异(q=0.625,P=0.685)。(2)准确性实验:两组条件下组Ⅰ和组Ⅱ的ROC曲线的AUC之间差异无统计学意义(P=1.000),实验组的组Ⅲ的AUC大于对照组(P=0.0379);对照组中8kPa和14kPa的SR值之间差异无统计学意义(P=0.258),对照组中8,45和80kPa之间,14,45和80kPa之间以及实验组中四种弹性模量的仿体SR值之间差异均有统计学意义(P0.001)。结论通过对RTE检查中的压力区间与压放频率进行定量控制来指导医师操作较使用压放推荐指标2-3可以提高其SR值测量重复性和准确性。
[Abstract]:Objective to investigate the effects of the pressure range and pressure-discharge frequency of the probe on the repeatability and accuracy of the strain ratio (SR) measurement in quantitative feedback controlled real-time tissue elastic imaging (RTE). Methods one FS01 pressure sensor was installed on both sides of Hitachi HI VISION preirus ultrasonic diagnostic instrument. The pressure feedback ultrasonic elastic imaging probe (hereinafter referred to as the pressure probe) is constructed. The elastic image and probe are applied to the "light pressure-decompression" pressure range and pressure-release frequency of the tissue through the image acquisition card and the data acquisition card in real time. Transmitted to the laptop operating panel for timely control and observation, Through this system, the probe pressure range and pressure-frequency can be adjusted in real time to obtain a satisfactory elastic imaging diagram. The repeatability and accuracy of the pressure probe were tested. The methods were as follows: (1) repetitive experiment: 15 operators with different proficiency performed three groups of RTE tests under different conditions for ultrasonic cylindrical phantom with Young's modulus of 80 kPa, diameter of 10.4 mm, center depth of 3 cm: group 1 as reference. The conventional method of pressure-setting recommendation index 2-3; Group 2 was examined by elastic imaging under the guidance of the pressure frequency of 1.5 times / s in the pressure range of 0 ~ 80 g, and group 3 under the guidance of 1.5 times / s in the pressure range of 40 ~ 120 g / s. The SR values of each group were measured in each group, the SR values of each group were measured 15 times, and the CV values of SR values were calculated for each group of physicians. (2) accuracy experiment: under the guidance of the recommended pressure-drop index 2-3 (control group) and the 0 ~ 100g pressure range 1.5 times / s pressure-release frequency (experimental group). The elastic modulus was (8 / 14 / 45 and 80kPa) and the strain ratio of cylindrical ultrasonic imitating body at 4 points of 3cm (diameter 10.4 mm, center depth) was measured 45 times for each hardness imitating body under the condition of (SR), group. The data were divided into three groups under each condition. The area (AUC), under the ROC curve of group 鈪，
本文编号：2233681
[Abstract]:Objective to investigate the effects of the pressure range and pressure-discharge frequency of the probe on the repeatability and accuracy of the strain ratio (SR) measurement in quantitative feedback controlled real-time tissue elastic imaging (RTE). Methods one FS01 pressure sensor was installed on both sides of Hitachi HI VISION preirus ultrasonic diagnostic instrument. The pressure feedback ultrasonic elastic imaging probe (hereinafter referred to as the pressure probe) is constructed. The elastic image and probe are applied to the "light pressure-decompression" pressure range and pressure-release frequency of the tissue through the image acquisition card and the data acquisition card in real time. Transmitted to the laptop operating panel for timely control and observation, Through this system, the probe pressure range and pressure-frequency can be adjusted in real time to obtain a satisfactory elastic imaging diagram. The repeatability and accuracy of the pressure probe were tested. The methods were as follows: (1) repetitive experiment: 15 operators with different proficiency performed three groups of RTE tests under different conditions for ultrasonic cylindrical phantom with Young's modulus of 80 kPa, diameter of 10.4 mm, center depth of 3 cm: group 1 as reference. The conventional method of pressure-setting recommendation index 2-3; Group 2 was examined by elastic imaging under the guidance of the pressure frequency of 1.5 times / s in the pressure range of 0 ~ 80 g, and group 3 under the guidance of 1.5 times / s in the pressure range of 40 ~ 120 g / s. The SR values of each group were measured in each group, the SR values of each group were measured 15 times, and the CV values of SR values were calculated for each group of physicians. (2) accuracy experiment: under the guidance of the recommended pressure-drop index 2-3 (control group) and the 0 ~ 100g pressure range 1.5 times / s pressure-release frequency (experimental group). The elastic modulus was (8 / 14 / 45 and 80kPa) and the strain ratio of cylindrical ultrasonic imitating body at 4 points of 3cm (diameter 10.4 mm, center depth) was measured 45 times for each hardness imitating body under the condition of (SR), group. The data were divided into three groups under each condition. The area (AUC), under the ROC curve of group 鈪，
本文编号：2233681
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