三维斑点追踪技术评价甲状腺功能亢进患者左心室收缩功能

发布时间：2018-09-11 08:37

【摘要】：目的应用三维斑点追踪技术定量评价甲状腺功能亢进患者不同时期左心室心肌收缩功能的改变。方法行常规及三维超声心动图检查,测量左心室射血分数(LVEF)、左心室心肌质量及左心室整体的峰值纵向应变(GLS)、圆周应变(GCS)、面积应变(GAS)及径向应变(GRS)。结果单纯甲亢A组与对照组相比,LVEF、左心室心肌质量无明显差异(P0.05),GLS、GCS、GAS及GRS值增加(P0.05)。单纯甲亢B组与对照组相比,GLS、GCS、GAS及GRS值减低(P0.05),左心室心肌质量增加(P0.05),而LVEF无明显差异(P0.05)。甲亢性心脏病组与单纯甲亢A、B组及对照组比较,LVEF、GLS、GCS、GAS及GRS值明显减低(P0.05,P0.01),左心室心肌质量增加(P0.05,P0.01)。结论甲状腺功能亢进患者在未出现心脏临床症状前,随时间推移,左心室心肌收缩功能由增强逐渐减低,收缩功能受损时,心肌质量增加,心脏发生重构。
[Abstract]:Objective to quantitatively evaluate the changes of left ventricular systolic function in patients with hyperthyroidism by three dimensional speckle tracing technique. Methods conventional and three-dimensional echocardiography were performed to measure left ventricular ejection fraction (LVEF), left ventricular mass, peak longitudinal strain, (GLS), circumferential strain, (GCS), area strain, (GAS) and radial strain (GRS). Results there was no significant difference in left ventricular mass between group A and control group (P0.05). The levels of GCSGAS and GRS in group A were significantly higher than those in group A (P0.05). Compared with the control group, the levels of GCSGAS and GRS in hyperthyroidism group B were decreased (P0.05), and the myocardial mass of left ventricle was increased (P0.05), but there was no significant difference in LVEF (P0.05). Compared with simple hyperthyroidism group and control group, the levels of GCSGAS and GRS in hyperthyroid heart disease group were significantly lower than those in simple hyperthyroidism group and control group (P0.05, P0.01), and left ventricular mass increased (P0.05, P0.01). Conclusion in hyperthyroidism patients, the left ventricular myocardial contractile function decreases gradually with time before the onset of clinical cardiac symptoms, and the myocardial mass increases and heart remodeling occurs when the systolic function is impaired.
【作者单位】：辽宁省金秋医院超声科;
【分类号】：R581.1;R540.45

【参考文献】