2D-STI与RT-3DE评估不同支数冠脉病变的冠心病患者左心室功能
发布时间：2018-09-18 15:23
【摘要】：目的： 应用二维斑点追踪（two-dimensional speckle tracking imaging,2D-STI）技术及实时三维超声心动图（real-time three-dimensional echocardiography,RT-3DE）技术对不同支数冠脉病变的冠心病患者左心室功能及所测参数相关性进行研究。 方法： 采用Philips IE33彩色多普勒超声诊断仪配套QLAB8.0定量分析软件中的2D-STI技术及RT-3DE技术对冠心病对照组(0组)27例、单支病变组（1组）34例、双支病变组（2组）28例、三支病变组（3组）25例、射血分数正常组（N组）48例、射血分数减低组（L组）39例进行检测分析。 测量各组RT-3DE参数：三维超声舒张末期容积(three dimensional enddiastolic volume,3DEDV)、三维超声收缩末期容积(three dimensional end systolicvolume,3DESV)、三维超声射血分数(three dimensional ejection fraction,3DEF)、经心率校正的16节段达最小收缩容积的时间标准差[Tmsv16-SD adjusted by theR-R interval, Tmsv16-SD(R-R%)]、经心率校正的16节段达最小收缩容积的时间最大差值[Tmsv16-Dif adjusted by the R-R interval, Tmsv16-dif(R-R%)]； 测量各组2D-STI参数：左室整体扭转角度峰值(peak twist, Ptw)、心底部旋转角度峰值(rotation on basal plane,PBR)、心尖部旋转角度峰值(rotation on apicalplane, PAR)。 0、1、2、3组之间两两比较RT-3DE各参数、2D-STI各参数；N组与L组之间比较RT-3DE各参数、2D-STI各参数，，并对各组2D-STI参数Ptw与RT-3DE参数3DEF、Tmsv16-SD(R-R%)的相关性进行分析。 结果： 1、0组、1组、2组、3组两两之间RT-3DE收缩功能参数3DEDV、3DESV、3DEF均有显著差异(P0.01)； 2、1组、2组、3组RT-3DE同步性参数Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)显著大于0组(P0.01)；3组RT-3DE同步性参数Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)显著大于1组(P0.01)；1组、2组之间与2组、3组之间RT-3DE同步性参数Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)差异均无统计学意义（P0.05）； 3、0组、1组、2组、3组之间2D-STI扭转参数PBR，差异均无统计学意义（P0.05）；2组、3组2D-STI扭转参数PAR、Ptw均低于0组(P0.05)；0组、1组之间2D-STI扭转参数PAR、Ptw差异均无统计学意义（P0.05）；1组、2组、3组之间2D-STI扭转参数PAR、Ptw差异均无统计学意义（P0.05）； 4、L组RT-3DE各参数3DEDV、3DESV、3DEF、Tmsv16-SD(R-R%)、Tmsv16-Dif(R-R%)及2D-STI参数PAR、Ptw与N组比较，均有显著差异(P0.01)；L组2D-STI参数PBR与N组相比较，差异无统计学意义（P0.05）； 5、0组、1组、2组、3组、N组、L组的2D-STI扭转角度Ptw与相应的RT-3DE参数3DEF、Tmsv16-SD(R-R%)相关性无统计学意义（P0.05）。 结论： 1、应用RT-3DE技术及2D-STI技术可以从射血分数、同步性、扭转角度等方面对不同支数冠脉病变的冠心病患者左心室功能进行评估。 2、本课题提示RT-3DE技术及2D-STI技术所测量部分参数[3DEF与Ptw、Tmsv16-SD(R-R%)与Ptw]之间相关性不显著。
[Abstract]:Objective: to study the correlation of left ventricular function and measured parameters in coronary heart disease patients with coronary artery disease by using two-dimensional speckle tracing (two-dimensional speckle tracking imaging,2D-STI) and real-time three-dimensional echocardiography (real-time three-dimensional echocardiography,RT-3DE). Methods: 27 cases of coronary heart disease (CHD) control group (group 0), 34 cases of single vessel disease group (group 1) and 28 cases of double vessel disease group (group 2) were treated by 2D-STI technique and RT-3DE technique in QLAB8.0 quantitative analysis software of Philips IE33 color Doppler ultrasound diagnostic instrument. There were 25 cases in three vessel lesion group (3 groups), 48 cases in normal ejection fraction group (N group) and 39 cases in low ejection fraction group (L group). The RT-3DE parameters of each group were measured as follows: Three-dimensional ultrasound end-diastolic volume (three dimensional enddiastolic volume,3DEDV), three-dimensional ultrasound end-systolic volume (three dimensional end systolicvolume,3DESV), three-dimensional ultrasound ejection fraction (three dimensional ejection fraction,3DEF). [Tmsv16-SD adjusted by theR-R interval, Tmsv16-SD (R-R%)], Tmsv16-Dif adjusted by the R-R interval, Tmsv16-dif (R-R%); 2D-STI parameters of each group were measured: left ventricular global torsion angle peak value (peak twist, Ptw), bottom rotation angle peak (rotation on basal plane,PBR), apex rotation angle peak (rotation on apicalplane, PAR). 01T 2T group compared RT-3DE parameters 2D-STI between two groups. The parameters of RT-3DE 2D-STI were compared between group N and group L, and the correlation between 2D-STI parameter Ptw and RT-3DE parameter 3DEFMS v16-SD (R-R%) was analyzed. Results: 1There were significant differences in the systolic function parameters of RT-3DE between two groups (P0.01), Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were significantly higher than those in 0 group (P0.01). The Tmsv16-SD (R-R%) Tmsv16-Dif (R-R%) of RT-3DE synchronization parameters in the three groups was significantly higher than that in the first group (P0.01) and the RT-3DE synchronization parameters Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were not significantly different between the two groups (P0.05). There was no significant difference in PBR, of 2D-STI torsion parameter between group 1 and group 2 (P0.05). The PAR,Ptw of 2D-STI torsion parameter in group 2 was lower than that in group 0 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 1 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 2 (P0.05), and there were significant differences in RT-3DE parameters between group N and group N (P0.01), between group C and group N (P0.01), and there were significant differences between group N and group N in RT-3DE parameters (3DEDVV / 3DESVV16-SD (R-R%), PAR,Ptw (R-R%) and PAR,Ptw in group N (P0.01). There was no significant difference between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%) (P0.05), and there was no significant correlation between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%). Conclusion: 1. RT-3DE and 2D-STI techniques can be used to measure the ejection fraction and synchronism. The left ventricular function of patients with coronary heart disease with different branches of coronary artery disease was evaluated from the angle of torsion. 2. This study suggests that there is no significant correlation between 3DEF and Ptw,Tmsv16-SD (R-R%) and Ptw in some parameters measured by RT-3DE and 2D-STI techniques.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R541.4;R540.45
本文编号：2248324
[Abstract]:Objective: to study the correlation of left ventricular function and measured parameters in coronary heart disease patients with coronary artery disease by using two-dimensional speckle tracing (two-dimensional speckle tracking imaging,2D-STI) and real-time three-dimensional echocardiography (real-time three-dimensional echocardiography,RT-3DE). Methods: 27 cases of coronary heart disease (CHD) control group (group 0), 34 cases of single vessel disease group (group 1) and 28 cases of double vessel disease group (group 2) were treated by 2D-STI technique and RT-3DE technique in QLAB8.0 quantitative analysis software of Philips IE33 color Doppler ultrasound diagnostic instrument. There were 25 cases in three vessel lesion group (3 groups), 48 cases in normal ejection fraction group (N group) and 39 cases in low ejection fraction group (L group). The RT-3DE parameters of each group were measured as follows: Three-dimensional ultrasound end-diastolic volume (three dimensional enddiastolic volume,3DEDV), three-dimensional ultrasound end-systolic volume (three dimensional end systolicvolume,3DESV), three-dimensional ultrasound ejection fraction (three dimensional ejection fraction,3DEF). [Tmsv16-SD adjusted by theR-R interval, Tmsv16-SD (R-R%)], Tmsv16-Dif adjusted by the R-R interval, Tmsv16-dif (R-R%); 2D-STI parameters of each group were measured: left ventricular global torsion angle peak value (peak twist, Ptw), bottom rotation angle peak (rotation on basal plane,PBR), apex rotation angle peak (rotation on apicalplane, PAR). 01T 2T group compared RT-3DE parameters 2D-STI between two groups. The parameters of RT-3DE 2D-STI were compared between group N and group L, and the correlation between 2D-STI parameter Ptw and RT-3DE parameter 3DEFMS v16-SD (R-R%) was analyzed. Results: 1There were significant differences in the systolic function parameters of RT-3DE between two groups (P0.01), Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were significantly higher than those in 0 group (P0.01). The Tmsv16-SD (R-R%) Tmsv16-Dif (R-R%) of RT-3DE synchronization parameters in the three groups was significantly higher than that in the first group (P0.01) and the RT-3DE synchronization parameters Tmsv16-SD (R-R%) and Tmsv16-Dif (R-R%) were not significantly different between the two groups (P0.05). There was no significant difference in PBR, of 2D-STI torsion parameter between group 1 and group 2 (P0.05). The PAR,Ptw of 2D-STI torsion parameter in group 2 was lower than that in group 0 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 1 (P0.05). There was no significant difference in 2D-STI torsion parameter PAR,Ptw between group 1 and group 2 (P0.05), and there were significant differences in RT-3DE parameters between group N and group N (P0.01), between group C and group N (P0.01), and there were significant differences between group N and group N in RT-3DE parameters (3DEDVV / 3DESVV16-SD (R-R%), PAR,Ptw (R-R%) and PAR,Ptw in group N (P0.01). There was no significant difference between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%) (P0.05), and there was no significant correlation between the 2D-STI torsion angle Ptw and the corresponding RT-3DE parameters (3DEFV / Tmsv16-SD (R-R%). Conclusion: 1. RT-3DE and 2D-STI techniques can be used to measure the ejection fraction and synchronism. The left ventricular function of patients with coronary heart disease with different branches of coronary artery disease was evaluated from the angle of torsion. 2. This study suggests that there is no significant correlation between 3DEF and Ptw,Tmsv16-SD (R-R%) and Ptw in some parameters measured by RT-3DE and 2D-STI techniques.
【学位授予单位】：南昌大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R541.4;R540.45
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