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双侧基底节筛孔状态的MRI表现及可能的临床意义

发布时间:2018-10-08 20:03
【摘要】:目的:探讨双侧基底节筛孔状态的MRI表现及可能的临床意义。方法:选取63例双侧基底节筛孔状态患者作为病例组,并通过MRI评价其病灶形态、信号特点;同时选取63例性别、年龄相匹配的正常志愿者作为对照组,病例组及对照组均进行中文版简易智能状态检查量表(MMSE)评分;并按性别分层,研究高血压与双侧基底节筛孔状态的关系。结果:所有病灶集中于双侧壳核、豆状核,且呈双侧对称性、筛孔状分布;病灶在T_2WI上呈高信号,T_1WI及FLAIR T_2WI上呈低信号,无明确壁或胶质增生表现,扩散未见明确受限表现。病例组的MMSE总评分[(26.00±1.95)分]较对照组[(28.44±1.15)分]低,且两者间差异具有统计学意义(Z=-7.15,P0.001)。分层χ2检验结果提示两性高血压与筛孔状态均存在相关性(χ_M~2=19.19,P_M0.001;χ_F~2=13.60,P_F=0.001)。结论:双侧基底节筛孔状态是一种病理改变,与患者认知功能损伤有一定关系,高血压可能是其中一个危险因素,应引起临床重视。
[Abstract]:Objective: to investigate the MRI findings of bilateral basal ganglia ethmoid foramen and its possible clinical significance. Methods: 63 patients with bilateral basal ganglia ethmoidal foramen were selected as the case group, and their lesion morphology and signal characteristics were evaluated by MRI, and 63 normal volunteers with gender and age matched were selected as the control group. Case group and control group were assessed with the Chinese version of simple Intelligent State examination scale (MMSE), and the relationship between hypertension and bilateral basal ganglia ethmoidal foramen was studied by sex stratification. Results: all the lesions were concentrated in the bilateral putamen nucleus, lentiform nucleus, with bilateral symmetry and ethmoidal foramen distribution, the lesions showed high signal intensity on T_2WI, low signal on T 1WI and FLAIR T_2WI, no clear wall or glial hyperplasia, and no definite limited manifestation of diffusion. The total score of MMSE in the case group [(26.00 卤1.95)] was lower than that in the control group [(28.44 卤1.15)], and the difference between the two groups was statistically significant (P 0.001). The results of stratified 蠂 2 test showed that there was a correlation between hypertension and sieve foramen (蠂 _ 2 / M _ (2) ~ (19.19) / P _ (M _ (0.001); 蠂 _ (2) S / F _ (13.60) / P _ (F _ (0.001). Conclusion: the condition of bilateral basal ganglia ethmoidal foramen is a pathological change, which is related to the cognitive impairment of patients. Hypertension may be one of the risk factors, which should be paid more attention to in clinic.
【作者单位】: 南方医科大学附属南海医院放射科;广东省医学科学院 广东省人民医院放射科;
【基金】:国家自然科学基金资助(81471654)
【分类号】:R445.2;R743


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