MRI引导放射治疗中电子回转效应的蒙特卡罗研究

发布时间：2018-10-10 20:38

【摘要】：为了研究磁共振引导放射治疗对剂量分布的影响,采用蒙特卡罗方法研究了横向均匀磁场对6 MV光子束在4种不同人体组织材料与空气界面处因电子回转效应导致剂量分布的改变。模拟显示,对于电离能相近的几种材料,磁场对剂量分布扰动的差别较小,而且电离能较大的材料,这种扰动明显变小。结果表明,磁场的引入会影响光子束原有的剂量分布,且这种影响与材料的电离能有关。这意味着虽然磁共振引导放射治疗可以增强靶向精度,提高治疗效果,但磁场会导致光子束剂量分布的改变,且不同的组织这种改变也不相同,这将为相应的剂量算法研究带来了新的挑战。
[Abstract]:In order to study the effect of magnetic resonance guided radiotherapy on dose distribution, Monte Carlo method was used to study the change of dose distribution of 6 MV photon beam at the interface between four different human tissue materials and air due to the electron rotation effect in the transverse uniform magnetic field. The simulation results show that for several materials with similar ionization energy, the difference of magnetic field to the dose distribution disturbance is small, and for the material with higher ionization energy, the disturbance becomes smaller obviously. The results show that the introduction of magnetic field will affect the original dose distribution of the photon beam, and this effect is related to the ionization energy of the material. This means that, while MR-guided radiotherapy can improve targeting accuracy and therapeutic effectiveness, magnetic fields can lead to changes in the dose distribution of photon beams, which vary from tissue to tissue. This will bring new challenges to the corresponding dose algorithm research.
【作者单位】：四川大学原子核科学技术研究所辐射物理及技术教育部重点实验室;第三军医大学大坪医院肿瘤放射治疗中心;
【基金】：国家科技支撑计划项目(2011BAI12B05,2012BAI15B01)~~
【分类号】：R730.55

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