超声引导下经皮微波消融治疗甲状腺良性结节疗效观察

发布时间：2018-10-23 10:03

【摘要】：目的探讨超声引导下经皮微波消融(MWA)治疗甲状腺良性结节的有效性和安全性。方法回顾性分析308例接受超声引导下经皮MWA治疗的甲状腺良性结节患者治疗及随访资料,观察术后并发症情况,记录并比较消融前结节体积及消融后结节体积及体积缩小率。结果对308例患者共324个结节均成功完成消融。术中及术后并发症患者经对症处理后均恢复正常。甲状腺结节消融前平均体积为(12.17±20.16)cm~3,最终消融后平均体积为(2.35±4.42)cm~3,较消融前差异有统计学意义(P0.01),最终消融后体积缩小率为(66.43±60.08)%。消融后1个月、3个月、6个月、12个月甲状腺结节体积均较消融前明显减小(P均0.05)。消融前结节体积与最终消融后结节体积缩小率呈正相关(r=0.181,P=0.001)。结论超声引导下经皮MWA治疗良性甲状腺结节疗效确切,且安全、微创。
[Abstract]:Objective to evaluate the efficacy and safety of ultrasound guided percutaneous microwave ablation (MWA) in the treatment of benign thyroid nodules. Methods the clinical data of 308 patients with benign thyroid nodules treated by ultrasound guided percutaneous MWA were retrospectively analyzed. The postoperative complications were observed and the volume and reduction rate of the nodules before and after ablation were recorded and compared. Results all 324 nodules of 308 patients were ablated successfully. Patients with intraoperative and postoperative complications returned to normal after symptomatic treatment. The mean volume of thyroid nodules before ablation was (12.17 卤20.16) cm~3, and the mean volume after ablation was (2.35 卤4.42) cm~3,. The volume reduction rate after ablation was (66.43 卤60.08)%. The volume of thyroid nodule at 1 month, 3 months, 6 months and 12 months after ablation was significantly smaller than that before ablation (P 0.05). There was a positive correlation between the nodule volume before ablation and the reduction rate of nodular volume after final ablation (r = 0.181, P < 0.001). Conclusion Ultrasound-guided percutaneous MWA is effective, safe and minimally invasive in the treatment of benign thyroid nodules.
【作者单位】：首都医科大学附属北京友谊医院超声科;
【分类号】：R581;R445.1

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