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超声弹性成像诊断乳腺癌腋窝淋巴结转移的价值研究

发布时间:2018-10-25 19:59
【摘要】:目的:探讨超声弹性成像技术(ultrasonic elastography,UE)及二维超声(Two-dimensional ultrasound,2D-US)对乳腺癌腋窝淋巴结(Axillary lymphnode,ALN)转移的诊断价值,提高超声对ALN转移状态的鉴别诊断水平。 方法:研究对象为2012年12月至2013年12月于广西医科大学第一附属医院胃肠腺体外科住院并接受手术治疗的女性乳腺癌患者共94例,对乳腺癌同侧ALN94枚行2D-US及UE检测,观察声像图特点,,测量大小、皮质厚并计算纵横比(Long diameter/short diameter ratio, L/S),行弹性评分。与术后病理结果对照分析,评价超声对乳腺癌患者同侧ALN转移状态的诊断价值。 结果:1.2D-US乳腺癌同侧转移性与非转移性ALN相比:淋巴结L/S<2.0;皮质增厚≥0.3cm;淋巴门消失,差异有统计学意义(P<0.05)。2.非转移性ALN的UE评分多为1、2分,转移性ALN多为3、4分。以UE≥3分为界值诊断ALN转移的灵敏度、特异度、准确率分别为84.31%(43/51)、81.40%(35/43)、82.98%(78/94)。2D-US、UE及二者联合诊断乳腺癌ALN转移的准确率分别为75.53%,82.98%,92.55%,二者联合诊断准确率高于二者单独应用,差异有统计学意义(P<0.05)。UE评分2、3分的ALN中,图像蓝色区域多出现在淋巴结周边,与淋巴结皮质对应,蓝色仅出现在皮质占80%(28/35),20%(7/35)皮质及髓质均出现蓝色,该部分ALN转移性与非转移性组蓝色分布差异无统计学意义(P>0.05)。 结论:UE对乳腺癌ALN转移状态的判断具有较高诊断价值,非转移性ALN的弹性评分以1、2分为主,转移性ALN以3、4分为主。2D-US联合UE检查能提高乳腺癌ALN转移诊断准确率,UE可作为诊断乳腺癌ALN转移的有临床价值的新方法。
[Abstract]:Objective: to evaluate the diagnostic value of ultrasound elastography (ultrasonic elastography,UE) and two-dimensional ultrasound (Two-dimensional ultrasound,2D-US) in axillary lymph node (Axillary lymphnode,ALN) metastasis of breast cancer. Methods: from December 2012 to December 2013, 94 female breast cancer patients were admitted to the first affiliated Hospital of Guangxi Medical University and underwent surgical treatment. 2D-US and UE were performed on ipsilateral ALN94 of breast cancer. The characteristics of sonogram were observed, the cortical thickness was measured and the aspect ratio (Long diameter/short diameter ratio, L / S) was calculated. To evaluate the diagnostic value of ultrasound in ipsilateral ALN metastasis of breast cancer patients. Results: the ipsilateral metastatic ALN of 1.2D-US breast cancer was: lymph node L / S < 2.0, cortical thickening 鈮

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