磁共振DWI联合DCE序列诊断早期强直性脊柱炎骶髂关节改变

发布时间：2018-11-11 21:05

【摘要】：目的:探讨磁共振DWI联合DCE-MRI诊断早期强直性脊柱炎的临床应用价值。方法:回顾性搜集48例临床早期活动性强直性脊柱炎患者影像资料,分析其DWI及DCE序列图像,分别测量骶侧髂侧关节面下骨髓的ADC值,并与21例健康志愿者的资料进行对比分析,计算增强因子Fenh、增强斜率Senh和达峰时间Tmax,并与正常组对照,绘制病例组时间-信号曲线(TIC),对ADC值与Fenh、Senh值之间关系进行统计学分析。结果:病例组髂骨侧关节面下骨髓区ADC平均值为(5.05±1.10)×10-4 mm2/s,骶骨侧为(4.63±0.79)×10-4 mm2/s,均较对照组增高;病例组骨髓区Fenh、Senh高于对照组,Tmax低于正常值;病例组TIC表现为Ⅱ型,Ⅲ型;病变区ADC值与Fenh值之间呈高度直线相关关系(P0.05),相关系数r=0.705。结论:磁共振DWI及DCE-MRI对早期AS患者骶髂关节骨髓异常改变显示敏感;病变区ADC值与Fenh值相结合,增强了早期诊断本病的信心,提供了影像诊断的新思路。
[Abstract]:Objective: to evaluate the clinical value of magnetic resonance (DWI) combined with DCE-MRI in the diagnosis of early ankylosing spondylitis (ankylosing spondylitis). Methods: the imaging data of 48 patients with active ankylosing spondylitis were collected retrospectively and their DWI and DCE sequences were analyzed. The ADC values of the sacral iliac subarticular bone marrow were measured respectively. The data of 21 healthy volunteers were compared and analyzed. The enhancement factor Fenh, enhancement slope Senh and peak time Tmax, were calculated and compared with the control group. The ADC value and Fenh, value of (TIC), were drawn. The relationship between Senh values was analyzed statistically. Results: the average value of ADC in the bone marrow area of the iliac side was (5.05 卤1.10) 脳 10 ~ (-4) mm2/s, in the case group and (4.63 卤0.79) 脳 10 ~ (-4) mm2/s, in the sacral side of the iliac bone side, which was higher than that in the control group. The Fenh,Senh of bone marrow area in the case group was higher than that of the control group, the Tmax was lower than the normal value; the TIC of the case group was type 鈪，

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