经胸超声心动图测定无冠状动脉狭窄的糖尿病患者左心室灌注量可行性的观察

发布时间：2018-11-12 19:18

【摘要】：目的探讨常规经胸超声心动图(TTE)评估糖尿病患者左心室整体灌注功能的可行性及其与糖尿病病程的相关性。方法选取经冠状动脉造影证实无冠状动脉狭窄的T2DM患者(T2DM组)60例和健康对照(NC)者60名。采用多普勒和三维超声心动图测量冠状窦血流和左心室质量(LVM)。左心室整体灌注量由冠状窦血流量除以LVM计算所得,并分析其与糖尿病病程的相关性。结果与NC组比较,T2DM组LVM增加[(154.35±19.44)vs(163.00±17.94)g,P0.05],静息时左心室灌注量减少[(6.04±4.77)vs(1.72±0.33)ml/(min·g),P0.01]。静息时左心室整体灌注量与糖尿病病程呈负相关(r=-0.533,P=0.000)。结论 TTE可有效地检测出经冠状动脉造影证实无冠状动脉狭窄的糖尿病患者在静息时存在冠状动脉微血管功能障碍。糖尿病患者的左心室整体灌注量减少,且与其糖尿病病程呈负相关。
[Abstract]:Objective to investigate the feasibility of conventional transthoracic echocardiography (TTE) in evaluating left ventricular global perfusion in diabetic patients and its correlation with the course of diabetes. Methods 60 patients with T2DM without coronary artery stenosis (T2DM group) and 60 healthy controls (NC) group) were selected. Measurement of Coronary Sinus Blood flow and left Ventricular Mass (LVM). By Doppler and Three-dimensional Echocardiography Global left ventricular perfusion was calculated by coronal sinus blood flow divided by LVM, and its correlation with the course of diabetes was analyzed. Results compared with NC group, LVM increased in T2DM group [(154.35 卤19.44) vs () 163.00 卤17.94], and left ventricular perfusion decreased at rest [(6.04 卤4.77) vs (1.72 卤0.33) ml/ (min g), P0.01]. Global left ventricular perfusion was negatively correlated with the course of diabetes at rest (r = -0.533P = 0.000). Conclusion TTE can effectively detect coronary microvascular dysfunction in patients with diabetes without coronary artery stenosis confirmed by coronary angiography. Global left ventricular perfusion decreased in diabetic patients and was negatively correlated with the course of diabetes.
【作者单位】：江苏省连云港市第一人民医院超声科;广东省第二人民医院超声科;
【分类号】：R587.2;R540.45

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