DWI在新生儿低血糖脑病中的诊断价值
发布时间：2018-11-14 12:06
【摘要】：目的:探讨DWI在新生儿低血糖脑病诊断中的应用价值。方法:回顾性分析18例经临床确诊的新生儿低血糖患儿的临床及MRI资料,所有患儿均行常规T1WI、T2WI及DWI检查,4例严重低血糖患儿另行氢质子磁共振波谱(1 H-MRS)检查。结果:MRI显示低血糖脑病呈弥漫性脑损伤改变,主要累及顶枕部16例,占88.89%(16/18);胼胝体压部12例,占66.67%(12/18);视辐射9例,占50%(9/18);内囊后肢8例,占44.44%(8/18)。额叶(4/18)、颞叶(3/18)、丘脑(3/18)及脑干(1/18)等部位亦累及。病变多呈稍长T1、稍长T2信号,DWI呈明显高信号。DWI异常信号的出现早于常规MRI序列,显示病灶的范围较常规序列广泛全面,尤其对胼胝体、内囊后肢、视辐射、丘脑等病灶的显示较常规序列敏感。4例日龄≥9d的低血糖脑病患儿,双侧顶枕叶、基底节及视辐射出现短T1、短T2信号,考虑为亚急性早期出血所致。4例MRS显示损伤部位出现倒置乳酸(Lac)峰,谷氨酸/肌酸比值(Glx/Cr)、胆碱/肌酸比值(Cho/Cr)明显增高,而N-乙酰天门冬氨酸/肌酸比值(NAA/Cr)明显降低。结论:MRI是新生儿低血糖脑病首选影像检查方法,以DWI序列优势最突出,不仅显示典型脑损伤部位的高信号,还能显示不典型部位的高信号。
[Abstract]:Objective: to evaluate the value of DWI in the diagnosis of neonatal hypoglycemia encephalopathy. Methods: the clinical and MRI data of 18 neonates with hypoglycemia confirmed by clinical diagnosis were retrospectively analyzed. Routine T 1WI T 2WI and DWI examination were performed in all children, and hydrogen proton magnetic resonance spectroscopy (1 H-MRS) was performed in 4 patients with severe hypoglycemia. Results: MRI showed diffuse brain injury in hypoglycemic encephalopathy, mainly involving the parietal occipital region in 16 cases (88.89%), the corpus callosum in 12 cases (66.67%), the visual radiation in 9 cases (50%), the corpus callosum in 12 cases (66.67%), the optic radiation in 9 cases (9 / 18). There were 8 cases (44.44%) with internal capsule hindlimb (8 / 18). The frontal lobe (4 / 18), the temporal lobe (3 / 18), the thalamus (3 / 18) and the brain stem (1 / 18) are also involved. The lesions showed longer T 1, longer T 2 signal and higher signal intensity in DWI. The abnormal signal of DWI appeared earlier than that of conventional MRI sequence, and the range of lesion was more extensive than that of conventional sequence, especially for corpus callosum, posterior limb of internal capsule, visual radiation. The display of hypoglycemic encephalopathy in 4 children with hypoglycemic encephalopathy 鈮，
本文编号：2331112
[Abstract]:Objective: to evaluate the value of DWI in the diagnosis of neonatal hypoglycemia encephalopathy. Methods: the clinical and MRI data of 18 neonates with hypoglycemia confirmed by clinical diagnosis were retrospectively analyzed. Routine T 1WI T 2WI and DWI examination were performed in all children, and hydrogen proton magnetic resonance spectroscopy (1 H-MRS) was performed in 4 patients with severe hypoglycemia. Results: MRI showed diffuse brain injury in hypoglycemic encephalopathy, mainly involving the parietal occipital region in 16 cases (88.89%), the corpus callosum in 12 cases (66.67%), the visual radiation in 9 cases (50%), the corpus callosum in 12 cases (66.67%), the optic radiation in 9 cases (9 / 18). There were 8 cases (44.44%) with internal capsule hindlimb (8 / 18). The frontal lobe (4 / 18), the temporal lobe (3 / 18), the thalamus (3 / 18) and the brain stem (1 / 18) are also involved. The lesions showed longer T 1, longer T 2 signal and higher signal intensity in DWI. The abnormal signal of DWI appeared earlier than that of conventional MRI sequence, and the range of lesion was more extensive than that of conventional sequence, especially for corpus callosum, posterior limb of internal capsule, visual radiation. The display of hypoglycemic encephalopathy in 4 children with hypoglycemic encephalopathy 鈮，
本文编号：2331112
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