超声血流向量成像分析慢性心力衰竭左心室流体力学变化

发布时间：2018-11-15 07:59

【摘要】：目的探讨慢性心力衰竭(CHF)患者左心室内血流自收缩射血向舒张充盈血流逆转的规律。资料与方法选取25例CHF患者作为CHF组,并选取28例健康人作为对照组。测定射血-充盈血流逆转间期(FRI)、校正射血-充盈血流逆转间期(CFRI)、射血-充盈血流逆转流率(FRR)、左心室射血期峰值流率(FRPE),比较两组左心室流体力学参数的差异。结果与对照组相比,CHF患者左心室涡流FRI延长[(71±13)ms对(113±30)ms,P0.05)],FRR减低[(46.85±21.35)cm2/s对(27.90±16.77)cm2/s,P0.05)],FRPE减低[(74.54±9.10)cm2/s对(41.12±17.25)cm2/s,P0.05)]。FRI、CFRI与Tei指数呈正相关(r=0.812、0.849,P0.01),FRI与左心室射血分数(LVEF)、短轴缩短率(FS)、每搏量(SV)、心输出量(CO)、心指数(CI)呈负相关(r=-0.646~-0.515,P0.05、P0.01);CFRI与LVEF、FS、SV、CO、CI呈负相关(r=-0.685~-0.456,P0.05、P0.01);FRR与Tei指数呈负相关(r=-0.604,P0.05),与LVEF、FS、SV、CO、CI呈正相关(r=0.503~0.812,P0.05、P0.01);FRPE与Tei指数呈负相关(r=-0.734,P0.01),与LVEF、FS、SV、CO、CI呈正相关(r=0.557~0.776,P0.05、P0.01)。结论超声血流向量成像能够直观地显示并定量分析CHF患者左心室的流体力学变化,左心室内血流方向逆转效率可以作为判断CHF治疗效果的指标之一。
[Abstract]:Objective to investigate the reversal of left ventricular autocontractile ejection to diastolic filling in patients with chronic heart failure (CHF). Materials and methods 25 CHF patients were selected as CHF group and 28 healthy persons as control group. (FRI), correction of ejection-filling reversal interval (CFRI), ejection-flow reversal rate (FRR), left ventricular peak flow rate (FRPE), To compare the difference of left ventricular hydrodynamic parameters between the two groups. Results compared with the control group, left ventricular eddy current FRI prolonged [(71 卤13) ms vs (113 卤30) ms,P0.05], FRR decreased [(46.85 卤21.35) cm2/s vs (27.90 卤16.77) cm2/s,P0.05] in CHF patients. FRPE decreased [(74.54 卤9.10) cm2/s vs (41.12 卤17.25) cm2/s,P0.05]. There was a positive correlation between FRI,CFRI and Tei index (r = 0.812 卤0.849), FRI and (LVEF), short axis shortening rate of left ventricular ejection fraction (FS),). There was a negative correlation between (CO), and (CI) in (SV), cardiac output per stroke volume (r = -0.646 ~ (-0.515) P _ (0.05) P _ (0.01). There was a negative correlation between CFRI and LVEF,FS,SV,CO,CI (r = -0.685U -0.456N, P 0.05, P 0.01). There was a negative correlation between FRR and Tei index (r = 0.604, P 0.05), and a positive correlation between FRR and LVEF,FS,SV,CO,CI (r = 0.503n, 0.812, P 0.05, P 0.01). There was a negative correlation between FRPE and Tei index (r = -0.734, P 0.01), and a positive correlation between FRPE and LVEF,FS,SV,CO,CI (r = 0.557, P = 0.776, P 0.05, P 0.01). Conclusion Ultrasound flow vector imaging can directly display and quantitatively analyze the changes of left ventricular fluid dynamics in patients with CHF, and the reversal efficiency of left ventricular flow direction can be used as an index to judge the therapeutic effect of CHF.
【作者单位】：同济大学附属东方医院心血管超声科;唐山市玉田县医院彩超室;大庆龙南医院物理诊断B超室;
【基金】：浦东新区科技发展基金创新项目(PKJ2010-Y16)
【分类号】：R445.1;R541.6

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