MRI联合超声诊断胎儿结节性硬化症

发布时间：2018-12-24 06:48

【摘要】：目的:探讨胎儿结节性硬化症(TSC)的产前MRI诊断方法及影像特征。方法:回顾性分析产前MRI联合超声诊断为TSC的14例胎儿资料,并总结其影像特征。MRI主要采用快速成像即HASTE序列及DWI序列,部分胎儿结合T1WI(FL2D)扫描。结果:产前超声筛查发现心脏横纹肌瘤胎儿共22例,MRI检查发现14例胎儿脑部见室管膜下结节,5例同时合并脑皮质结节。14例胎儿均诊断为TSC。胎儿脑部结节表现为T1WI稍高信号,HASTE序列低信号结节,以HASTE序列显示最佳。本组14例TSC胎儿9例终止妊娠引产,其中2例引产后标本解剖病检,证实为心脏横纹肌瘤伴颅内结节;5例出生后随访证实为TSC。结论:产前超声检查可准确诊断胎儿心脏横纹肌瘤。超声提示心脏横纹肌瘤后,MRI对诊断胎儿TSC颅脑病变敏感性高。MRI联合超声可以确诊胎儿TSC。
[Abstract]:Objective: to investigate the prenatal MRI diagnosis and imaging features of fetal nodular sclerosis (TSC). Methods: the data of 14 fetuses diagnosed as TSC by prenatal MRI combined with ultrasound were analyzed retrospectively and their imaging features were summarized. MRI was performed with HASTE sequence and DWI sequence, and some fetuses were scanned with T1WI (FL2D). Results: there were 22 cases of cardiac transverse leiomyoma detected by prenatal ultrasound, 14 cases of fetal brain were found to have subependymal nodules by MRI, 5 cases were complicated with cortical nodules. 14 cases were diagnosed as TSC.. Fetal brain nodules showed slightly hyperintense T1WI and hypointense nodules with HASTE sequence, and HASTE sequence was the best. In this study, 9 cases of TSC fetus terminated pregnancy induced labor, of which 2 cases were anatomical examination after induced labor, confirmed as cardiac transverse leiomyoma with intracranial nodules, and 5 cases were confirmed as TSC. at postnatal follow-up. Conclusion: prenatal ultrasound can accurately diagnose fetal cardiac transverse leiomyoma. MRI is highly sensitive to the diagnosis of fetal TSC craniocerebral lesions after transversal leiomyoma. MRI combined with ultrasound can diagnose fetal TSC..
【作者单位】：湖北省妇幼保健院放射科;湖北省妇幼保健院超声科;华润武钢二医院放射科;
【分类号】：R445.1;R445.2;R714.5

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