23例脑部多形性黄色星形细胞瘤的MRI分型对比研究

发布时间：2018-12-29 10:24

【摘要】：目的探讨脑部多形性黄色星形细胞瘤(PXA)不同影像学类型间的临床、MRI及病理特点。方法回顾性分析经手术病理证实的23例脑部PXA(囊性型12例,实性型11例)患者术前MRI、临床及病理资料,比较两型病变在发病年龄、瘤体大小、瘤周水肿程度、发病部位、恶性率等方面的差别。结果囊性型PXA患者的发病年龄平均(19±7.2)岁,实性型患者的发病年龄平均为(32±9.7)岁,两者发病年龄差异有统计学意义(P=0.002);囊性型PXA病变体积中位数为113902.1 mm3,明显大于实性型(45731.75 mm3,P=0.000)。两型病变在发病部位、瘤周水肿程度方面差异无统计学意义(P=0.427,P=1.000)。病理上,囊性型恶性率为25%(3/12),实性型恶性率为9%(1/11)。结论 PXA在不同影像学类型的表现有一定程度的差异,这或许有助于该病的分层治疗。
[Abstract]:Objective to investigate the clinical, MRI and pathological features of (PXA) in cerebral pleomorphic astrocytoma. Methods the clinical and pathological data of 23 patients with PXA (cystic type 12 cases, solid type 11 cases) confirmed by operation and pathology were analyzed retrospectively. The age of onset, the size of tumor body, the degree of edema around the tumor and the location of the disease were compared between the two types of lesions. A difference in the rate of malignancy, etc. Results the mean age of onset of cystic PXA was (19 卤7.2) years old, and that of solid type patients was (32 卤9.7) years old. The age difference between the two groups was statistically significant (P0. 002). The median volume of cystic PXA lesions was 113902.1 mm3, significantly larger than that of solid type (45731.75 mm3,P=0.000). There was no significant difference in the extent of edema around the tumor between the two types of lesions (P < 0. 427, P = 1. 000). Pathologically, the malignant rate of cystic type was 25% (3 / 12) and that of solid type was 9% (1 / 11). Conclusion there are some differences in the manifestations of PXA in different imaging types, which may be helpful to the treatment of the disease by stratification.
【作者单位】：广州市第一人民医院放射科;广州市南沙中心医院影像科;首都医科大学附属天坛医院神经影像中心;
【基金】：国家自然科学基金面上项目(编号:81271541)
【分类号】：R739.41;R445.2

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