原发性甲状旁腺功能亢进症PET-CT表现1例

发布时间：2019-01-04 07:11

【摘要】：目的:探讨原发性甲状旁腺功能亢进症(primary hyperparathyroidism,p HPT)18-氟-2-脱氧葡萄糖[2-(fluorine-18)-fluoro-2-deoxy-D-glucose,18F-FDG]正电子发射断层显像/计算机断层成像(positron emission tomography/computed tomography,PET-CT)的表现及PET-CT在p HPT中的作用。方法:回顾分析1例经病理确诊为甲状旁腺双腺瘤继发p HPT患者的PET-CT表现,并复习有关文献,对原发甲旁亢的PET-CT表现进行总结。结果:PET-CT发现甲状腺右叶下极后方两枚较肌肉密度稍低结节影,边界清楚,密度均匀,糖代谢轻度增高,全身多发骨质破坏伴糖代谢增高,骨质破坏边界清楚,18F-FDG最大标准摄取值达10。结论:PET-CT对p HPT的诊断有重要作用,可以准确发现全身各部位的骨质破坏及其程度,同时可以在术前进行甲状旁腺病变的定位诊断,为临床治疗提供更好依据。甲状旁腺瘤切除后,也可用PET/CT扫描来观察患者治疗后棕色瘤中成骨细胞的变化。
[Abstract]:Objective: to investigate 18- (fluorine-18)-fluoro-2-deoxy-D-glucose, in primary hyperparathyroidism (primary hyperparathyroidism,p HPT) Positron emission tomography (18F-FDG) / computed tomography (positron emission tomography/computed tomography,PET-CT) and the role of PET-CT in p HPT. Methods: the PET-CT findings of a patient with p HPT secondary to parathyroid adenoma confirmed by pathology were retrospectively analyzed and the related literatures were reviewed. The PET-CT findings of primary hyperparathyroidism were summarized. Results: PET-CT showed that the right inferior lobe of the thyroid gland had a slightly lower nodular density than that of the muscle, with a clear boundary, a homogeneous density, a slight increase in glucose metabolism, multiple bony destruction in the whole body with increased glucose metabolism, and a clear bone destruction boundary. The maximum standard uptake of 18F-FDG is 10. 5%. Conclusion: PET-CT plays an important role in the diagnosis of p HPT. It can accurately detect the extent of bone destruction in all parts of the body, and can also be used for the localization diagnosis of parathyroid lesions before operation, which provides a better basis for clinical treatment. After parathyroid tumor resection, PET/CT scan can also be used to observe the changes of osteoblasts in brown tumor after treatment.
【作者单位】：中南大学湘雅二医院PET/CT中心;
【分类号】：R582.1;R817.4

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