头部位移对纵向研究波谱结果可重复性的影响

发布时间：2019-02-15 22:23

【摘要】：目的探讨不同形式位移经校正后对MRS结果可重复性的影响。方法纳入20名被试者于无位移、平动位移、平动-转动位移时分别进行MRS扫描,每次间隔10min,位移状态扫描前由SPM软件自动获取VOI位置,测量并比较平动位移、平动-转动位移经校正后VOI内N-乙酰天门冬氨酸(NAA)、肌酸(Cr)、磷酸肌酸(PCr)和胆碱复合物(Cho)含量及NAA/(Cr+PCr)和Cho/(Cr+PCr);计算上述参数位移对比无位移时差异性系数(CV)和重复性指数(RI)。结果平动位移经校正后各参数与无位移间差异均无统计学意义(P均0.05),平动-转动位移经校正后除Cr外,NAA、Cho、NAA/Cr+PCr、Cho/Cr+PCr与无位移间差异均有统计学意义(P均0.01)。平动位移和平动-转动位移经校正后与无位移时比较,NAA、Cho、Cr含量及NAA/(Cr+PCr)、Cho/(Cr+PCr)的平均CV均12%,重复性可接受;RI值除Cr外,余参数均20%,重复性可接受。结论 MRS中对患者头部平动位移可准确校正,所得结果重复性较好。
[Abstract]:Objective to investigate the effect of different displacement forms on repeatability of MRS results after correction. Methods Twenty subjects were scanned with MRS at the time of no displacement, translational displacement and rotational displacement. The VOI position was automatically obtained by SPM software before the displacement state scan, and the translational displacement was measured and compared. The content of N-acetylaspartate (NAA), creatine (Cr), creatine (PCr) and choline complex (Cho) and NAA/ (Cr PCr) and Cho/ (Cr PCr); in VOI after translational and rotational displacement correction The difference coefficient (CV) and repeatability index (RI). When calculating the displacement comparison of the above parameters and no displacement Results there was no significant difference between the parameters of the translational displacement and the non-displacement after correction (P 0.05). After the correction of the translational and rotational displacement, NAA,Cho,NAA/Cr PCr, was obtained except for Cr. There was significant difference between Cho/Cr PCr and no displacement (P0.01). The NAA,Cho,Cr content and the average CV of NAA/ (Cr PCr), Cho/ (Cr PCr) were 12, and repeatability was acceptable, compared with those without displacement after the correction of the translational displacement and the dynamic-rotational displacement. With the exception of Cr, the RI values were 20 and the repeatability was acceptable. Conclusion the head displacement can be corrected accurately in MRS, and the results are reproducible.
【作者单位】：同济大学附属同济医院医学影像科;上海市磁共振重点实验室;
【分类号】：R445.2

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