血管内超声在急性冠脉综合征中的运用价值
发布时间:2019-02-16 16:02
【摘要】:目的通过分析急性冠脉综合征患者冠状动脉造影(CAG)及血管内超声(IVUS)检查数据,探讨血管内超声在定量分析冠状动脉临界病变管腔狭窄率,斑块性质,进一步治疗和评价经皮冠状动脉介入(PCI)治疗效果中作用。研究血管内超声(IVUS)在急性冠脉综合征(ACS)临界病变中的应用价值。 材料与方法1)对2010年1月至2014年3月大同市三医院心内科32例根据临床表现诊断为ACS患者,其中男21例(65.63%),女11例(34.37%),年龄32~73岁,平均年龄(58.1±10.4)岁,均行冠状动脉造影评估每一位患者左主干(LM)、左前降支(LAD)、左回旋支(LCX)、右冠状动脉(RCA)的管腔狭窄情况;2)冠状动脉造影发现的狭窄≥70%的病变直接行PCI,临界病变血管段进行IVUS检测,观察血管壁的形态结构,分析动脉粥样硬化斑块的类型、性质及其狭窄程度,对符合PCI干预指征的病变行PCI术,其余患者予药物保守治疗;3)PCI术后行IVUS检查即刻评价支架置入是否理想、是否合并手术并发症。 结果1)32例患者中CAG发现冠脉血管12支17处病变管腔直径狭窄率≥70%,予直接行支架植入术,共植入17枚支架;2)CAG测得38处管腔直径狭窄率为50-70%(临界病变),经IVUS测得有33处病变管腔狭窄率≥70%,涉及28位患者,共置入33枚支架,单支架23例,双支架5例;3)CAG与IVUS检测的38处临界病变处直径狭窄率及管腔面积狭窄率(斑块负荷)比较,IVUS测值显著高于CAG测值,统计学上有显著性差异(P0.01);4)术后行IVUS检查示均显示支架完全贴壁、扩张充分、展开均匀、完全覆盖病变,未发现冠脉内夹层形成、壁内血肿、支架断裂等PCI术后并发症;5)另外5处病变涉及4例患者因行IVUS检查结果未达支架植入标准,予药物治疗。 结论1)CAG不同程度地低估了冠状动脉临界病变狭窄,IVUS与CAG相比发现的临界病变管腔狭窄率诊断更精确。2)IVUS对斑块定性较CAG更优。3)更能准确选择临界病变支架置入的适应证。4)IVUS能进一步明确冠状动脉临界病变的性质和狭窄程度并能指导临床治疗,安全性高,在冠心病介入治疗中发挥重要作用。
[Abstract]:Objective to study the quantitative analysis of coronary artery stenosis rate and plaque character in patients with acute coronary syndrome by coronary angiography (CAG) and intravascular ultrasound (IVUS). Further treatment and evaluation of percutaneous coronary intervention (PCI) effect. To study the application value of intravascular ultrasound (IVUS) in critical lesions of (ACS) in acute coronary syndrome (ACS). Materials and methods 1) from January 2010 to March 2014, 32 patients with ACS were diagnosed in Department of Cardiology, three Hospitals of Datong City, including 21 males (65.63%) and 11 females (34.37%), aged 32 to 73 years. The mean age was (58.1 卤10.4) years. Coronary angiography was performed to evaluate the stenosis of left anterior descending (LAD), left circumflex (LAD), (LCX), right coronary (RCA) in each patient. 2) the stenosis 鈮,
本文编号:2424608
[Abstract]:Objective to study the quantitative analysis of coronary artery stenosis rate and plaque character in patients with acute coronary syndrome by coronary angiography (CAG) and intravascular ultrasound (IVUS). Further treatment and evaluation of percutaneous coronary intervention (PCI) effect. To study the application value of intravascular ultrasound (IVUS) in critical lesions of (ACS) in acute coronary syndrome (ACS). Materials and methods 1) from January 2010 to March 2014, 32 patients with ACS were diagnosed in Department of Cardiology, three Hospitals of Datong City, including 21 males (65.63%) and 11 females (34.37%), aged 32 to 73 years. The mean age was (58.1 卤10.4) years. Coronary angiography was performed to evaluate the stenosis of left anterior descending (LAD), left circumflex (LAD), (LCX), right coronary (RCA) in each patient. 2) the stenosis 鈮,
本文编号:2424608
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