体素内不相干运动MRI评估子宫肌瘤血流灌注及分子扩散状态的观察者间一致性

发布时间：2019-02-19 20:22

【摘要】：目的探讨体素内不相干运动(IVIM)MRI评估子宫肌瘤血流灌注及分子扩散状态的不同观察者间的一致性。方法采用3.0T MR仪对23例子宫肌瘤患者进行T2WI及多b值DWI。2名观察者利用后处理软件选择子宫肌瘤最大层面勾画ROI,使用双指数模型,生成IVIM MRI相关的参数图(D图、D*图、f图),得到数值分布的直方图,分别计算各参数的位于直方图左侧第25%、50%、75%位置的数值及平均值,比较2名观察者测量数据的一致性。结果23例子宫肌瘤患者中,2名观察者对12例选择最大层面的结果一致;2名观察者间测得的23例子宫肌瘤的D_(mean)、D25、DS0、D75值平均值差值为0~0.07 mm~2/s,f_(mean)、f25、f50、f75值平均值差值为0~0.01,D_(mean)*、D*25、D*50、D*75值平均值差值为0~5.38 mm~2/s;2名观察者测量的25个IVIM MRI参数的ICC值0.9,测量的33个IVIM MRI参数的ICC值0.8。结论采用IVIM MRI评估子宫肌瘤血流灌注及分子扩散状态的不同观察者间的一致性好,这种方法可行。
[Abstract]:Objective to investigate the consistency between different observers of voxel incoherent motion (IVIM) MRI) in assessing blood perfusion and molecular diffusion of uterine leiomyoma. Methods using 3.0T MR instrument, 23 patients with uterine leiomyoma were treated with T2WI and DWI.2 with multiple b values. Using post-processing software, the maximum level of uterine myoma was selected to draw a double-index ROI, model, and a IVIM MRI related parameter map (D) was generated. A histogram of numerical distribution is obtained, and the values and mean values of the parameters at the 25th 50% position on the left side of the histogram are calculated respectively, and the consistency of the measured data of two observers is compared. Results of the 23 patients with uterine leiomyoma, 2 observers were consistent in choosing the largest level for 12 cases. In 23 cases of uterine leiomyoma, the average difference of D _ (mean), D _ 25D _ D _ 0 D _ 75 was 0 ~ 0.07 mm~2/s,f_ (mean), f _ 25 F _ 50 ~ F _ 75 = 0 ~ 0. 01 D _ (mean) *, D ~ (25). The average value difference of DJ50 / DN75 is 0 / 5.38 mm~2/s;. The ICC value of 25 IVIM MRI parameters measured by two observers was 0.9.The ICC value of 33 IVIM MRI parameters measured was 0.8. Conclusion there is good consistency among different observers in evaluating the blood flow perfusion and molecular diffusion of uterine leiomyoma by IVIM MRI, and this method is feasible.
【作者单位】：北京大学第一医院医学影像科;
【分类号】：R445.2;R737.33

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