斑点追踪技术评价左心室构型正常的高血压患者心肌舒缩功能
发布时间：2019-03-08 15:25
【摘要】：目的应用斑点追踪成像技术(speckle tracking imaging, STI)评价构型正常的原发性高血压患者早期左心室心肌的舒缩功能。 方法选取左心室充盈正常的高血压患者40例(A组),左心室松弛性减低的高血压患者40例(B组),健康对照者30例(正常对照组),应用STI分别测量左心室长轴切面、心尖四腔心切面、两腔心切面整体心肌和心内膜下心肌基底段、中间段、心尖段收缩期长轴应变率(GSrL S),舒张早期长轴应变率(GSrL E),房缩期长轴应变率(GSrL A),通过左心室短轴心底水平和心尖水平分别计算心底水平旋转角度峰值(MV-Prot)、心尖水平旋转角度峰值(AP-Prot)、扭转角度峰值(Ptw)、收缩末期扭转角度(AVCtw)、等容舒张末期扭转角度(MVOtw)、等容解扭转率(UntwR)、解旋减半时间(UHT)等左心室扭转-解旋参数。 结果与正常对照组相比,A组患者心内膜下心肌收缩期应变率减低(P0.01),心内膜下心肌和整体心肌舒张早期应变减低(P0.05),房缩期心内膜下心肌应变增高(P0.05),心底水平旋转角度峰值、心尖水平旋转角度峰值、扭转角度峰值,收缩期末扭转角度、等容舒张期末扭转角度增加(P0.05),等容解扭转率减低(P0.05),解扭转减半时间延长(P0.05)；B组患者较正常对照组收缩期应变减低(P0.05),舒张期早期应变减低(P0.05),房缩期应变增高(PO.05),心底水平旋转角度峰值、心尖水平旋转角度峰值、扭转角度峰值、收缩期末扭转角度、等容舒张期末扭转角度增加(P0.05),等容解扭转率减低(P0.05),解扭转减半时间延长(P0.05)。与A组相比,B组患者心尖水平旋转角度峰值进一步增加(P0.05),等容解扭转率进一步减低(P0.05)。 结论应用STI技术通过检测左心室长轴心内膜下心肌的应变率和扭转、解旋参数可以定量分析左心室心肌的应变情况,准确评价原发性高血压患者左心室心肌功能的早期损伤。
[Abstract]:Objective to evaluate the diastolic and contractile function of left ventricular myocardium in hypertensive patients with normal configuration by dot tracing imaging (speckle tracking imaging, STI). Methods 40 hypertensive patients with normal left ventricular filling (group A), 40 hypertensive patients with impaired left ventricular relaxation (group B) and 30 healthy controls (normal control group) were selected. Left ventricular long axis sections were measured by STI. Apical four-chamber section, two-chamber section of the whole myocardium and subendocardial myocardial basal segment, middle segment, apical segment systolic long-axis strain rate (GSrL S), early diastolic long-axis strain rate (GSrL E), atrial contraction long-axis strain rate (GSrL A), The peak values of basal horizontal rotation angle (MV-Prot), apical horizontal rotation angle (AP-Prot), torsion angle peak (Ptw), end systolic torsion angle (AVCtw), were calculated from the left ventricular short axis bottom level and apical level, respectively. Isovolemic end-diastolic torsion angle (MVOtw), isovolumetric solution torsion rate (UntwR), deconvolution half-time (UHT) and other left ventricular torsion-deconvolution parameters. Results compared with the normal control group, the systolic strain rate of subendocardial myocardium and the early diastolic strain of subendocardial and global myocardium in group A were lower (P0.01), and that in group A was lower than that in control group (P0.05). During atrial contraction period, the subendocardial myocardial strain increased (P0.05), the peak of the horizontal rotation angle at the bottom of the heart, the peak of the horizontal rotation angle of the apex, the peak of the torsion angle, the torsion angle at the end of contraction, and the end-torsion angle at the end of isovolumetric relaxation (P0.05). The isovolumetric solution torsion rate was decreased (P0.05), and the solution torsion reduced half time was prolonged (P0.05); In group B, systolic strain decreased (P0.05), early diastolic strain decreased (P0.05), atrial contraction strain increased (PO.05), the peak of horizontal rotation angle of the heart floor, the peak of horizontal rotation angle of heart tip, and the peak of horizontal rotation angle of heart tip were observed in group B as compared with the normal control group (P0.05). The peak torsion angle, the torsion angle at the end of contraction, the torsion angle at the end of isovolumetric relaxation were increased (P0.05), the rate of isovolemic solution torsion was decreased (P0.05), and the half-time of solution torsion was prolonged (P0.05). Compared with group A, the peak of horizontal rotation angle of heart tip in group B was further increased (P0.05), and the torsion rate of isometric solution was further decreased (P0.05). Conclusion the strain rate and torsion of left ventricular long axis subendocardial myocardium can be measured by STI technique and the strain of left ventricular myocardium can be quantitatively analyzed and the early injury of left ventricular function can be accurately evaluated in patients with essential hypertension.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R544.1;R540.45
本文编号：2436941
[Abstract]:Objective to evaluate the diastolic and contractile function of left ventricular myocardium in hypertensive patients with normal configuration by dot tracing imaging (speckle tracking imaging, STI). Methods 40 hypertensive patients with normal left ventricular filling (group A), 40 hypertensive patients with impaired left ventricular relaxation (group B) and 30 healthy controls (normal control group) were selected. Left ventricular long axis sections were measured by STI. Apical four-chamber section, two-chamber section of the whole myocardium and subendocardial myocardial basal segment, middle segment, apical segment systolic long-axis strain rate (GSrL S), early diastolic long-axis strain rate (GSrL E), atrial contraction long-axis strain rate (GSrL A), The peak values of basal horizontal rotation angle (MV-Prot), apical horizontal rotation angle (AP-Prot), torsion angle peak (Ptw), end systolic torsion angle (AVCtw), were calculated from the left ventricular short axis bottom level and apical level, respectively. Isovolemic end-diastolic torsion angle (MVOtw), isovolumetric solution torsion rate (UntwR), deconvolution half-time (UHT) and other left ventricular torsion-deconvolution parameters. Results compared with the normal control group, the systolic strain rate of subendocardial myocardium and the early diastolic strain of subendocardial and global myocardium in group A were lower (P0.01), and that in group A was lower than that in control group (P0.05). During atrial contraction period, the subendocardial myocardial strain increased (P0.05), the peak of the horizontal rotation angle at the bottom of the heart, the peak of the horizontal rotation angle of the apex, the peak of the torsion angle, the torsion angle at the end of contraction, and the end-torsion angle at the end of isovolumetric relaxation (P0.05). The isovolumetric solution torsion rate was decreased (P0.05), and the solution torsion reduced half time was prolonged (P0.05); In group B, systolic strain decreased (P0.05), early diastolic strain decreased (P0.05), atrial contraction strain increased (PO.05), the peak of horizontal rotation angle of the heart floor, the peak of horizontal rotation angle of heart tip, and the peak of horizontal rotation angle of heart tip were observed in group B as compared with the normal control group (P0.05). The peak torsion angle, the torsion angle at the end of contraction, the torsion angle at the end of isovolumetric relaxation were increased (P0.05), the rate of isovolemic solution torsion was decreased (P0.05), and the half-time of solution torsion was prolonged (P0.05). Compared with group A, the peak of horizontal rotation angle of heart tip in group B was further increased (P0.05), and the torsion rate of isometric solution was further decreased (P0.05). Conclusion the strain rate and torsion of left ventricular long axis subendocardial myocardium can be measured by STI technique and the strain of left ventricular myocardium can be quantitatively analyzed and the early injury of left ventricular function can be accurately evaluated in patients with essential hypertension.
【学位授予单位】：青岛大学
【学位级别】：硕士
【学位授予年份】：2014
【分类号】：R544.1;R540.45
【参考文献】
相关期刊论文 前7条
1 王志斌,田玉聚;硫氮怡酮对心肌梗塞患者左室舒张和充盈动力学的急性效应[J];青岛医学院学报;1991年02期
2 韩伟;谢明星;王新房;吕清;;Assessment of Left Ventricular Global Twist in Essential Hypertensive Heart by Speckle Tracking Imaging[J];Journal of Huazhong University of Science and Technology(Medical Sciences);2008年01期
3 谢冰;许迪;陆凤翔;姚静;吴红平;雍永宏;曹克将;;二维应变超声成像技术评价心力衰竭患者左心功能的初步研究[J];中华医学超声杂志(电子版);2011年12期
4 刘国仗,马文君;高血压诊断和治疗研究进展[J];中华心血管病杂志;2003年12期
5 谢明星;张丽;吕清;王新房;韩伟;张静;刘莹莹;付倩;项飞翔;;超声二维斑点追踪显像技术评价肥厚型心肌病左心室旋转和扭转运动[J];中国医学科学院学报;2008年01期
6 韩伟;谢明星;张丽;王静;吕清;;超声斑点追踪显像技术评价高血压对左室心肌扭转-位移环的影响[J];中国医学影像技术;2007年11期
7 李真真;王志斌;孙品;聂晶;李艳;付秀秀;张金慧;;二维应变成像技术评价左心室构型正常高血压患者的心肌功能[J];中华医学超声杂志(电子版);2013年01期
，本文编号：2436941
本文链接：https://www.wllwen.com/yixuelunwen/fangshe/2436941.html
