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乳腺浸润性导管癌时间-信号强度曲线及ADC值与病理学分级的相关性

发布时间:2019-03-14 21:08
【摘要】:目的探讨浸润性导管癌(IDC)时间-信号强度曲线(TIC)及ADC值与组织学分级的相关性。方法回顾性分析43例(共45个病灶)经病理学证实为IDC的动态增强MRI及DWI表现,测量肿块的早期强化率、ADC值,描绘时间-信号强度曲线(TIC),对不同病理学分级IDC的早期强化率、TIC曲线分型及ADC值进行组间比较,并分析其与病理组织分级的相关性。结果 43例IDC中,Ⅰ级8例,Ⅱ级24例,Ⅲ级11例。不同级别IDC两两比较,早期强化率的差异均无统计学意义(P均0.05),而TIC曲线分型、ADC值的差异均有统计学意义(P均0.05),IDC的TIC曲线分型与病理组织学分级呈正相关关系(r=0.40,P0.01),与ADC值呈负相关(r=-0.79,P0.01)。正常乳腺组织与不同病理组织分级IDC的ADC值差异均有统计学意义(P均0.05)。结论乳腺动态增强MRI的TIC曲线结合ADC值可在一定程度上预测IDC的组织学分级。
[Abstract]:Objective to investigate the correlation between (IDC) time-signal intensity curve (TIC) and ADC value and histological grade in invasive ductal carcinoma. Methods the dynamic enhanced MRI and DWI findings of 43 patients (45 lesions) proved by pathology were retrospectively analyzed. The early enhancement rate, ADC value and time-signal intensity curve (TIC),) of 43 patients with IDC were measured. The early enhancement rate, TIC curve type and ADC value of IDC in different pathological grades were compared among groups, and the correlation between them and pathological grade was analyzed. Results in 43 cases of IDC, 8 cases were grade 鈪,

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