二维超声、实时组织弹性成像及声触诊组织量化技术诊断乳腺浸润性导管癌

发布时间：2019-04-02 12:58

【摘要】：目的探讨二维超声(2D-US)、实时组织弹性成像(UE)及声触诊组织量化(VTQ)技术对乳腺浸润性导管癌(IDC)的诊断价值。方法对188例患者共213个乳腺病灶术前分别行2D-US、UE及VTQ检查,对各病灶2D-US声像图表现进行超声乳腺影像报告数据系统(BI-RADS-US)分类,UE采用5级评分法判断结节性质,VTQ技术定量测定结节内剪切波速度(SWV)。绘制ROC曲线,比较2D-US、UE、SWV曲线下面积(AUC)。结果 2D-US诊断IDC的敏感度为82.35%(126/153),特异度为71.67%(43/60),准确率为79.34%(169/213)。UE诊断IDC的敏感度为86.27%(132/153),特异度为73.33%(44/60),准确率为82.63%(176/213)。良性及恶性结节的SWV别为(3.09±1.26)m/s、(6.83±2.18)m/s(P0.05);以3.59m/s作为诊断恶性病灶的最佳截断值,VTQ诊断IDC的敏感度为86.93%(133/153),特异度为76.67%(46/60),准确率为84.04%(179/213)。2D-US、UE、SWV诊断乳腺IDC的AUC分别为0.811、0.843、0.899,差异有统计学意义(P0.01)。结论 US、UE及VTQ均有助于鉴别诊断乳腺良性结节及乳腺IDC,UE优于2DUS,VTQ可获得客观的量化指标,重复性好,优于UE和2D-US。
[Abstract]:Objective to evaluate the diagnostic value of two-dimensional ultrasound (2D-US), real-time tissue elastography (UE) and palpation tissue quantification (VTQ) in invasive ductal carcinoma of the breast (IDC). Methods two hundred and thirteen breast lesions in 188 patients were examined by 2D US, UE and VTQ before operation. The sonographic features of each lesion were classified by BI-RADS-US (Ultrasonography report data system), and all the lesions were divided into two groups by ultrasound imaging report system (BI-RADS-US). UE was used to evaluate the nature of nodules by grade 5 score, and the (SWV). Of internal shear wave velocity was quantitatively measured by VTQ technique. Draw the ROC curve to compare the area under the 2D, UE, (AUC). Curve Results the sensitivity, specificity and accuracy of 2D-US were 82.35% (126 / 153), 71.67% (43 / 60), 79.34% (169 / 213), 86.27% (132 / 153), 86.27% (132 / 153), respectively. The specificity and accuracy were 73.33% (44 / 60) and 82.63% (176 / 213) respectively. The SWV of benign and malignant nodules were (3.09 卤1.26) m / s, (6.83 卤2.18) m / s (P0.05). The sensitivity, specificity and accuracy of 3.59m/s in diagnosing malignant lesions were 86.93% (133 / 153), 76.67% (46 / 60) and 84.04% (179 / 213) respectively, and the sensitivity, specificity and accuracy of VTQ were 86.93% (133 / 153), 76.67% (46 / 60) and 84.04% (179 / 213) respectively. The AUC of SWV in diagnosis of breast IDC were 0.811, 0.843 and 0.899, respectively, and the difference was statistically significant (P0.01). Conclusion both US,UE and VTQ are helpful for the differential diagnosis of benign breast nodules and breast IDC,UE, which is superior to 2DUS.VTQ can obtain objective quantitative indexes with good repeatability, and is superior to UE and 2D US.
【作者单位】：石河子大学医学院第一附属医院功能科;
【分类号】：R737.9;R445.1

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