初步探讨MRI与PET-CT诊断肝脏泡状棘球蚴病的应用价值

发布时间：2019-04-29 18:18

【摘要】：目的:探讨核磁共振与PET-CT诊断肝脏泡状棘球蚴病(HAE)的应用价值。方法:回顾性分析经手术病理证实为HAE且同时行MR常规扫描和PET-CT检查的14例患者资料。14例HAE患者共检出30个病灶,按照Kodama的MRI分型分为5种类型,分别观察MRI和PET-CT表现,并根据MRI和PET-CT结果对HAE病灶的生物学活性进行定性评估。对MRI和PET-CT结果进行一致性分析,计算Kappa值。结果:(1)MRI表现:30个HAE病灶最大径平均值约为14.59cm,1型1个病灶,2型9个病灶,3型10个病灶,4型10个病灶。(2)PET-CT表现:30个HAE病灶中,16个病灶显示18F脱氧葡萄糖(18F-FDG)在病灶边缘呈不同程度摄取,其中1、2、3型(20个病灶)共有15个病灶显示18F脱氧葡萄糖(18F-FDG)呈不同程度摄取,4型10个病灶中有1个病灶显示18F脱氧葡萄糖(18F-FDG)呈高摄取。14例共30个病灶通过MRI和PET-CT对病灶生物学活性评估的一致性较好(Kappa=0.59,P0.01)。结论:基于MRI图像有无小囊泡显示可以反映HAE是否存在生物学活性。
[Abstract]:Objective: to evaluate the value of magnetic resonance imaging (MRI) and PET-CT in the diagnosis of hepatic alveolar echinococcosis (HAE). Methods: the data of 14 patients with HAE confirmed by surgery and pathology were retrospectively analyzed. 14 patients with HAE were divided into 5 types according to the MRI classification of Kodama, 30 lesions were detected by routine MR scanning and PET-CT examination, the patients were divided into 5 types according to the MRI classification of Kodama, and 30 lesions were detected in 14 patients with HAE. The features of MRI and PET-CT were observed, and the biological activity of HAE lesions was evaluated qualitatively according to the results of MRI and PET-CT. The consistency of MRI and PET-CT results was analyzed and the Kappa value was calculated. Results: (1) MRI findings: the maximum diameter of 30 HAE lesions was 14.59 cm, 1 focus of type 1, 9 lesions of type 2, 10 lesions of type 3, 10 lesions of type 4. (2) PET-CT findings: of the 30 lesions of HAE, there were 1 focus of type 1, 9 lesions of type 2, 10 lesions of type 4. Sixteen lesions showed 18F-deoxyglucose (18F-FDG) uptake in different degrees at the edge of the lesion, of which 15 lesions showed different uptake of 18F-deoxyglucose (18F-FDG) in 1,2,3-type (20 lesions). One of the 10 lesions of type 4 showed high uptake of 18F-deoxyglucose (18F-FDG), and a total of 30 lesions in 14 cases had a good consistency (Kappa=0.59,P0.01) in evaluating the biological activity of the lesions by MRI and PET-CT. Conclusion: the presence or absence of vesicles in MRI images can reflect the biological activity of HAE.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R532.32;R817.4;R445.2

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