系统性红斑狼疮患者颈动脉内中膜厚度与血清高敏CRP的关系
发布时间:2019-05-23 06:40
【摘要】:目的探讨系统性红斑狼疮(SLE)患者颈动脉内中膜厚度(IMT)、外周血高敏C反应蛋白(hs-CRP)的表达水平及两者相关性。方法超声检查70例SLE女性患者(IMT≥1.0mm者12例为IMT阳性组;IMT1.0mm者58例为IMT阴性组)及40例健康女性的颈动脉IMT,并用ELISA测定其血清hs-CRP水平,分析两者相关性。结果 (1)SLE组(包括IMT阳性组及IMT阴性组)hs-CRP水平高于对照组(P0.05),IMT阳性组hs-CRP水平高于IMT阴性组(P0.05);(2)SLE组IMT与病程及hs-CRP水平呈正相关(分别为r=0.743,P0.001及r=0.827,P0.001);(3)根据ROC曲线,当hs-CRP在4.44mg/L时诊断指数最大(0.815),灵敏度和特异度分别为91.7%和89.8%。结论颈动脉IMT联合hs-CRP检测可作为SLE患者早期动脉粥样硬化的一项预测方法。
[Abstract]:Objective to investigate the expression of Gao Min C-reactive protein (hs-CRP) in peripheral blood of patients with carotid intima-media thickness (IMT),) in patients with systemic lupus erythematosus (SLE). Methods the carotid IMT, of 70 female patients with SLE (IMT 鈮,
本文编号:2483684
[Abstract]:Objective to investigate the expression of Gao Min C-reactive protein (hs-CRP) in peripheral blood of patients with carotid intima-media thickness (IMT),) in patients with systemic lupus erythematosus (SLE). Methods the carotid IMT, of 70 female patients with SLE (IMT 鈮,
本文编号:2483684
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