弹性成像应变率比值法评价血栓硬度与短期溶栓效果的相关性研究
发布时间：2019-05-26 19:36
【摘要】：目的应用超声弹性成像技术评价下肢深静脉血栓硬度,探讨血栓硬度与短期溶栓效果间的相关性及应变率比值法在预测溶栓效果中的应用价值。方法对63例急性下肢深静脉血栓患者行超声弹性成像(UE)检查并测定应变率比值(SR);经过10d的抗凝、溶栓治疗,根据治疗效果不同,将其分为治愈组、治疗有效组、治疗无效组,比较各组间血栓SR的差异;将血栓SR与治疗是否有效对照,构建受试者工作特征曲线(ROC)并确定溶栓是否有效的SR临界值。结果 (1)血栓硬度与溶栓效果具有一定相关性。治愈组及治疗有效组的血栓SR明显小于治疗无效组。治愈组与治疗有效组间血栓SR无明显差异。(2)血栓SR可以预测溶栓治疗效果。以SR1.36预测治疗有效,以SR≥1.36预测治疗无效,其灵敏度、特异度、准确度分别为88.9%、94.4%、93.7%。结论血栓硬度与溶栓效果具有一定相关性,超声弹性成像应变率比值法可以用来评价血栓硬度并预测治疗效果。
[Abstract]:Objective to evaluate the hardness of deep venous thrombosis of lower extremity by ultrasonic elastic imaging, to explore the correlation between thrombus hardness and short-term thrombolysis effect, and to explore the value of strain rate ratio method in predicting the effect of deep venous thrombosis. Methods 63 patients with acute deep venous thrombosis of lower extremity were examined by ultrasonic elastic imaging (UE) and the strain rate ratio (SR);) was measured. After 10 days of anticoagulant and thrombolysis therapy, according to the different therapeutic effects, it was divided into cure group, effective group and ineffective group, and the difference of thrombus SR among groups was compared. Compared with whether thrombus SR was effective or not, the working characteristic curve (ROC) of the subjects was constructed and the critical value of SR was determined whether the thrombus was effective or not. Results (1) there was a certain correlation between thrombus hardness and thrombolysis effect. The thrombus SR in the healing group and the effective group was significantly lower than that in the ineffective group. There was no significant difference in thrombus SR between cured group and effective group. (2) thrombus SR could predict the effect of thrombus therapy. SR1.36 was effective in predicting treatment, and SR 鈮，
本文编号：2485581
[Abstract]:Objective to evaluate the hardness of deep venous thrombosis of lower extremity by ultrasonic elastic imaging, to explore the correlation between thrombus hardness and short-term thrombolysis effect, and to explore the value of strain rate ratio method in predicting the effect of deep venous thrombosis. Methods 63 patients with acute deep venous thrombosis of lower extremity were examined by ultrasonic elastic imaging (UE) and the strain rate ratio (SR);) was measured. After 10 days of anticoagulant and thrombolysis therapy, according to the different therapeutic effects, it was divided into cure group, effective group and ineffective group, and the difference of thrombus SR among groups was compared. Compared with whether thrombus SR was effective or not, the working characteristic curve (ROC) of the subjects was constructed and the critical value of SR was determined whether the thrombus was effective or not. Results (1) there was a certain correlation between thrombus hardness and thrombolysis effect. The thrombus SR in the healing group and the effective group was significantly lower than that in the ineffective group. There was no significant difference in thrombus SR between cured group and effective group. (2) thrombus SR could predict the effect of thrombus therapy. SR1.36 was effective in predicting treatment, and SR 鈮，
本文编号：2485581
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