1.5T DWI在肺内良、恶性病变鉴别诊断中最适b值的探讨
发布时间：2019-06-17 17:11
【摘要】：目的:探讨1.5TDWI对肺内良、恶性病变的鉴别诊断价值及b值的优化。方法:搜集40例经病理/临床证实的肺内良、恶性病变患者(恶性病变23例,良性病变17例)的影像及临床资料,40例均经MSCT检查发现肺部病变,并行常规T1WI、T2WI以及多b值DWI(b=0,300,600,1000s/mm2)检查,测量3组b值测得的ADC值,分析不同b值对图像质量、信噪比(SNR)、对比噪声比(CNR)的影响,根据受试者工作特征(ROC)曲线评价不同b值下ADC值鉴别肺部良、恶性病变的诊断效能;并比较同一b值下良、恶性病变ADC值的差异。结果:随着b值的增加,DWI图像信号逐渐增高,ADC、SNR及CNR值逐渐下降;b值为300和600s/mm2两组图像SNR值差异无统计学意义(P0.05),b值为300与1000s/mm2以及600与1000s/mm2两组SNR值差异均具有统计学意义(P均0.05);CNR值在两两组间的差异均具有统计学意义(P均0.05)。b值为300、600和1000s/mm2时,ROC的曲线下面积(AUC)分别为0.78、0.83和0.81,且均具有诊断意义(AUC均0.5),当b=600s/mm2时,诊断效能最高。在同一b值下,恶性病变图像信号高于良性病变,且ADC值低于良性病变(P均0.05)。结论:1.5T DWI多b值胸部扫描有助于鉴别肺内良、恶性病变,当b=600s/mm2时,对肺良、恶性病变的鉴别诊断效能最高。
[Abstract]:Objective: To study the value of 1.5TDWI in the differential diagnosis of benign and malignant lesions of the lung and the optimization of the b-value. Methods: The images and clinical data of 40 cases of benign and malignant lesions (23 cases of malignant lesions and 17 benign lesions) in 40 cases of benign and malignant lesions of the lung were collected, and 40 cases were examined by MSCT to find the lung lesions, the normal T1WI, T2WI and the multi-b value DWI (b = 0,300,600,1000 s/ mm2). The effect of different b-value on image quality, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) was measured by measuring the ADC value measured in the 3-group b-value. The difference of the ADC values of benign and malignant lesions in the same b-value was compared. Results: With the increase of b value, the signal of DWI was gradually increased, and the value of ADC, SNR and CNR decreased gradually. The difference of SNR between the two groups with a value of 300 and 600 s/ mm2 was not statistically significant (P0.05), and the b value was 300 and 1000 s/ mm2 and the difference of SNR values between 600 and 1000s/ mm2 had statistical significance (P <0.05). The value of CNR was statistically significant between the two groups (P <0.05). The area under the curve of the ROC (AUC) was 0.78, 0.83, and 0.81, respectively, with a b value of 300,600 and 1000 s/ mm2, and the diagnostic efficacy was the highest when b = 600 s/ mm2. At the same b value, the malignant lesion image signal was higher than the benign lesion and the ADC value was lower than the benign lesion (P 0.05). Conclusion: The chest scan of 1.5T DWI multi-b value can be used to identify the benign and malignant lesions of the lung, and when b = 600 s/ mm2, the differential diagnosis of the benign and malignant lesions of the lung is the highest.
【作者单位】： 中国医科大学附属第四医院放射科;
【基金】：辽宁省自然科学基金资助项目(201302/035)
【分类号】：R734.2;R445.2
[Abstract]:Objective: To study the value of 1.5TDWI in the differential diagnosis of benign and malignant lesions of the lung and the optimization of the b-value. Methods: The images and clinical data of 40 cases of benign and malignant lesions (23 cases of malignant lesions and 17 benign lesions) in 40 cases of benign and malignant lesions of the lung were collected, and 40 cases were examined by MSCT to find the lung lesions, the normal T1WI, T2WI and the multi-b value DWI (b = 0,300,600,1000 s/ mm2). The effect of different b-value on image quality, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) was measured by measuring the ADC value measured in the 3-group b-value. The difference of the ADC values of benign and malignant lesions in the same b-value was compared. Results: With the increase of b value, the signal of DWI was gradually increased, and the value of ADC, SNR and CNR decreased gradually. The difference of SNR between the two groups with a value of 300 and 600 s/ mm2 was not statistically significant (P0.05), and the b value was 300 and 1000 s/ mm2 and the difference of SNR values between 600 and 1000s/ mm2 had statistical significance (P <0.05). The value of CNR was statistically significant between the two groups (P <0.05). The area under the curve of the ROC (AUC) was 0.78, 0.83, and 0.81, respectively, with a b value of 300,600 and 1000 s/ mm2, and the diagnostic efficacy was the highest when b = 600 s/ mm2. At the same b value, the malignant lesion image signal was higher than the benign lesion and the ADC value was lower than the benign lesion (P 0.05). Conclusion: The chest scan of 1.5T DWI multi-b value can be used to identify the benign and malignant lesions of the lung, and when b = 600 s/ mm2, the differential diagnosis of the benign and malignant lesions of the lung is the highest.
【作者单位】： 中国医科大学附属第四医院放射科;
【基金】：辽宁省自然科学基金资助项目(201302/035)
【分类号】：R734.2;R445.2
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相关期刊论文 前8条
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