三维彩色直方图在鉴别甲状腺良恶性结节中的应用

发布时间：2019-07-05 16:17

【摘要】：目的：探讨三维能量多普勒血管成像直方图血流定量分析在甲状腺结节良恶性鉴别诊断中的应用价值。方法：回顾性分析63例患者的69个甲状腺结节,以病理结果为金标准分为良性病变组及恶性病变组,用三维彩色直方图血流定量分析比较两组甲状腺结节定量指标：血管指数(vascularization index,VI)、血流指数(flow index,FI).血管血流指数(vascularization flow index,VFI),重复取样3次,取平均值,并探讨这些指标对鉴别甲状腺结节良、恶性的诊断价值。结果：所收集的三维多普勒数据经重建处理后均获得了较满意的三维能量多普勒图像,经统计学分析后,结果表明甲状腺恶性结节内血流量多于良性结节,恶性结节的血管指数(vascularization index, VI)、血流指数(flow index,FI).血管血流指数(vascularization flow index,VFI)均高于良性结节,良性病变组与恶性病变组之间的差异均有统计学意义(P0.05), ROC曲线分析结果显示VI、FI、VFI对甲状腺结节良恶性鉴别诊断均有效,以VI≥0.07为截值诊断甲状腺结节的良恶性,敏感度为97.6%,特异度为71.4%；以FI≥22.67为截值诊断甲状腺结节的良恶性,敏感度为80.5%,特异度为82.1%；以VFI≥1.86为截值诊断甲状腺结节的良恶性,敏感度为87.8%,特异度为78.6%。结论：三维彩色直方图血流定量分析在鉴别诊断甲状腺良恶性肿瘤中有较高的应用价值,可以作为鉴别甲状腺良恶性肿瘤的定量分析依据。
[Abstract]:Objective: to evaluate the value of three dimensional power Doppler angiography histogram flow quantitative analysis in the differential diagnosis of benign and malignant thyroid nodules. Methods: 69 thyroid nodules in 63 patients were analyzed retrospectively. according to the pathological results, they were divided into benign lesion group and malignant lesion group. The quantitative indexes of thyroid nodules in the two groups were compared by three-dimensional color histogram blood flow quantitative analysis: vascular index (vascularization index,VI) and blood flow index (flow index,FI). Vascular blood flow index (vascularization flow index,VFI), repeated sampling for 3 times, the average value was taken, and the diagnostic value of these indexes in differential diagnosis of benign and malignant thyroid nodules was discussed. Results: the three-dimensional Doppler data were reconstructed and satisfactory three-dimensional power Doppler images were obtained. after statistical analysis, the results showed that the blood flow in malignant thyroid nodules was higher than that in benign nodules, and the vascular index (vascularization index, VI), blood flow index (flow index,FI) of malignant nodules was higher than that of benign nodules. The vascular blood flow index (vascularization flow index,VFI) was higher than that of benign nodules. The difference between benign lesion group and malignant lesion group was statistically significant (P 0.05), ROC curve analysis showed that VI,FI,VFI was effective in the differential diagnosis of benign and malignant thyroid nodules. The sensitivity and specificity of VI 鈮，

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