1.5T ~1H-MRS在正常胰腺中的应用

发布时间：2019-07-16 18:15

【摘要】：目的:探讨1.5T氢质子磁共振波谱成像(MRS)在活体正常胰腺中的应用价值及影响因素。方法:采用单体素点分辨波谱(PRESS)序列采集20例健康志愿者的正常胰腺波谱,分析脂质峰高(Lip)、峰下面积、脂质峰下面积(Lip)/组织内水峰下面积(InW)比值与年龄、身高体重指数(BMI)的相关性,分析胆固醇和不饱和脂肪酸的混合峰下面积(Chol+UnSat)/脂质峰下面积(Lip)比值与年龄、BMI的相关性。结果:1.5T活体胰腺MRS扫描成功率为90%(18/20)。Lip峰、TMA峰和Chol+UnSat混合峰显示率分别为100.0%(18/18)、89%(16/18)和100%(18/18)。Lip峰高与年龄、BMI呈正相关(r=0.715、0.356),有统计学意义(P=0.01、0.047),峰下面积与年龄、BMI呈正相关(r=0.503、0.135),与年龄有统计学意义(P=0.033),与BMI无统计学意义(P=0.593)。Lip/InW比值与年龄、BMI呈正相关(r=0.718、0.563),有统计学意义(P=0.01、0.015)。(Chol+Unsat)/Lip比值与年龄、BMI呈正相关(r=0.762、0.520),有统计学意义(P=0.000、0.027)。Chol+Unsat峰下面积与年龄、BMI呈正相关(r=0.519、0.466),有统计学意义(P=0.004、0.000)。结论:1.5T磁共振波谱成像能够用于检测正常活体胰腺的主要代谢物并分析其谱线形态。
[Abstract]:Objective: to investigate the application value and influencing factors of 1.5T proton magnetic resonance spectroscopy (MRS) in normal pancreas in vivo. Methods: the normal pancreatic spectra of 20 healthy volunteers were collected by monomeric point-resolved spectrum (PRESS) sequence. the correlation between the area under lipid peak height (Lip), peak area, (Lip) / tissue water peak area (InW) ratio and age, body mass index (BMI), cholesterol and saturated fatty acid mixed peak area (Chol UnSat) / lipid subpeak area (Lip) ratio and age were analyzed. The correlation of BMI. Results: the success rate of 1.5T living pancreas MRS scan was 90% (18 鈮，

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