糖尿病患者医院获得性肺炎危险因素病例对照研究

发布时间：2018-02-23 07:26

本文关键词： 型糖尿病医院获得性肺炎危险因素病例对照研究　出处：《中华医院感染学杂志》2014年07期 　论文类型：期刊论文

【摘要】：目的探讨糖尿病住院患者医院获得性肺炎的危险因素,以达到指导糖尿病患者防治肺部感染的目的。方法以某综合性三级甲等医院2010-2011年2型糖尿病合并医院获得性肺炎患者100例为病例组,同时期入院的2型糖尿病未发生感染者为对照组,进行1∶1配对病例对照研究;单因素分析采用χ2检验,多因素分析采用条件logistic多元回归分析。结果 2型糖尿病患者1 022例,共发现100例医院获得性肺炎患者,感染率为9.8%;经单因素分析发现18个暴露因素是糖尿病住院患者获得性肺炎的关联因素;条件logistic回归分析筛选出低血清白蛋白、餐后2h血糖、促胃动力药是糖尿病住院患者获得性肺炎的主要危险因素(OR值分别为3.14、3.10、10.05,P0.05)。结论糖尿病住院患者合并医院获得性肺炎的影响因素较多,应密切注意患者的营养状况,纠正低血清白蛋白、控制血糖水平、合理应用抗菌药物、提高患者自身抵抗力,从而降低医院获得性肺炎的发生。
[Abstract]:Objective to explore the risk factors of nosocomial pneumonia in diabetic inpatients. Methods 100 patients with type 2 diabetes mellitus complicated with nosocomial pneumonia in a general Grade 3A hospital were selected as the case group. A 1: 1 matched case-control study was carried out in non-infected patients with type 2 diabetes mellitus in the same period, 蠂 2 test was used for univariate analysis and conditional logistic multivariate regression analysis was used for multivariate analysis. Results 1 022 patients with type 2 diabetes mellitus were included in the study. A total of 100 patients with nosocomial pneumonia were found to have an infection rate of 9.8%, 18 exposure factors were found to be the associated factors of acquired pneumonia in patients with diabetes mellitus by univariate analysis, low serum albumin and 2 h postprandial blood glucose were screened by conditional logistic regression analysis. Gastric motility drugs were the main risk factors of acquired pneumonia in patients with diabetes mellitus and their OR values were 3.14 ~ 3.10 ~ (10) ~ (10.05) (P < 0.05) respectively. Conclusion there are many influencing factors in diabetic inpatients with hospital acquired pneumonia, and the nutritional status of the patients should be paid close attention to. In order to reduce the incidence of hospital acquired pneumonia, the low serum albumin was corrected, the level of blood sugar was controlled, the antibiotics were used rationally, and the patient's resistance was improved.
【作者单位】：福建医科大学省立临床医学院;福建省立医院呼吸内科;
【基金】：福建省自然科学基金资助项目(2012Y0016)
【分类号】：R563.1

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