纤维支气管镜肺灌洗对机械通气患者肺部感染的疗效研究

发布时间：2018-03-19 21:53

本文选题：机械通气　切入点：肺部感染　出处：《中华医院感染学杂志》2016年02期 　论文类型：期刊论文

【摘要】：目的分析纤维支气管镜肺灌洗应用于机械通气发生肺部感染患者的临床疗效。方法选择2012年1月-2014年12月医院ICU住院的机械通气合并肺部感染的患者90例,根据患者入住ICU时间顺序分为研究组与对照组,各45例,研究组给予纤维支气管镜肺灌洗治疗,对照组给予常规的吸痰治疗,对比两组患者在治疗前感染程度及治疗后7d的临床疗效;采用SPSS18.0对数据进行统计分析。结果患者治疗后总有效率研究组为93.33%,对照组为82.22%,研究组总有效率显著升高,差异有统计学意义(P0.05);治疗前两组患者感染程度对比差异无统计学意义,治疗后7d研究组患者感染程度显著改善,与对照组对比差异有统计学意义(P0.05);研究组患者在纤维支气管镜肺灌洗后1h的PaO_2、PaCO_2、SaO_2显著改善,差异有统计学意义(P0.05)。结论纤维支气管镜肺灌洗应用于机械通气发生肺部感染患者的治疗安全有效,并能显著改善患者的动脉血气。
[Abstract]:Objective to analyze the clinical effect of bronchofiberscope lung lavage in patients with pulmonary infection caused by mechanical ventilation. Methods from January 2012 to December 2014, 90 cases of mechanical ventilation complicated with pulmonary infection in hospital ICU were selected. The patients were divided into study group (n = 45) and control group (n = 45) according to the time of admission to ICU. The study group was treated with bronchofibroscope lung lavage, and the control group was treated with routine sputum aspiration. Results the total effective rate was 93.33 in the study group and 82.22 in the control group, and the total effective rate in the study group was significantly higher than that in the control group. There was no significant difference in the degree of infection between the two groups before treatment, and the degree of infection in the study group was significantly improved 7 days after treatment. Compared with the control group, there was a significant difference between the two groups (P 0.05), and the patients in the study group had a significant improvement in the Pao _ 2C _ 2O _ 2 after one hour of bronchofiberoscopic lung lavage. Conclusion Pulmonary lavage with fiberoptic bronchoscopy is safe and effective in the treatment of pulmonary infection in patients with mechanical ventilation and can significantly improve arterial blood gas in patients with pulmonary infection.
【作者单位】：杭州师范大学附属医院呼吸科;杭州师范大学附属医院ICU;
【基金】：浙江省医药科技基金资助项目(201466009)
【分类号】：R563.1

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