自拟理肺化瘀方辅助治疗支气管哮喘发作期的效果及机制

发布时间：2018-03-20 14:05

本文选题：支气管哮喘　切入点：自拟理肺化瘀方　出处：《山东医药》2015年29期 　论文类型：期刊论文

【摘要】：目的观察自拟理肺化瘀方辅助治疗支气管哮喘发作期的效果,并探讨其可能的作用机制。方法选择支气管哮喘发作期患者102例,随机分为观察组、对照组各51例。对照组采用常规治疗,观察组在常规治疗的基础上加用自拟理肺化瘀方,两组均治疗12周。观察两组的治疗效果及检测治疗前后血清环磷酸腺苷(c AMP)水平。结果治疗结束后,对照组总有效率为76.5%,观察组为96.1%,两组比较,P0.05。对照组治疗前后血清c AMP水平分别为(11.56±3.91)、(19.96±4.61)μmol/L,观察组分别为(12.06±3.75)、(27.15±5.24)μmol/L;与治疗前比较,两组治疗后血清c AMP水平均明显升高(P均0.05),但观察组治疗后血清c AMP水平升高更明显(P0.05)。结论理肺化瘀方辅助治疗支气管哮喘发作期效果明显,其机制可能与改善患者β受体功能有关。
[Abstract]:Objective to observe the effect and possible mechanism of self-made Lifei Huayu recipe in treating bronchial asthma. Methods 102 patients with bronchial asthma were randomly divided into observation group. The control group (51 cases) was treated with routine therapy, while the observation group was treated with self-made prescription of "Lifei Huayu" on the basis of routine treatment. Both groups were treated for 12 weeks. The therapeutic effect and the level of serum adenosine monophosphate (AMP) before and after treatment were observed. The total effective rate was 76.5g / L in the control group and 96.1渭 mol / L in the observation group. The serum c AMP levels in the control group were 11.56 卤3.91 渭 mol / L before and after treatment, and in the observation group were 12.06 卤3.75 渭 mol / L, 27.15 卤5.24 渭 mol / L, respectively. After treatment, the level of serum c AMP was significantly increased in both groups (P < 0.05), but the level of serum c AMP was significantly increased after treatment in the observation group (P < 0.05). Conclusion Lifei Huayu prescription is effective in the treatment of bronchial asthma. The mechanism may be related to the improvement of 尾-receptor function in patients.
【作者单位】：唐山市丰润区第二人民医院;
【基金】：河北省中医药学会科学技术奖(20142046)
【分类号】：R562.25

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