无创呼吸机在呼吸衰竭经鼻气管插管患者行有创机械通气的可行性研究

发布时间：2018-06-18 22:15

本文选题：呼吸功能不全 + 无创呼吸机　；参考：《中国全科医学》2017年S1期

【摘要】：目的探讨无创呼吸机在呼吸衰竭经鼻气管插管患者行有创机械通气的可行性。方法选取2014年9月—2016年9月在南阳医专第一附属医院治疗的150例呼吸衰竭患者,其均经鼻气管插管行有创机械通气。将使用无创呼吸机通气治疗的80例患者设为观察组,未采用无创呼吸机治疗的70例患者设为对照组。监测两组血液pH值、动脉血氧分压(PaO_2)、动脉血二氧化碳分压(PaCO_2);比较两组ICU住院时间、通气时间以及住院费用,并比较两组患者呼吸机相关性肺炎发生率及脱机成功率。结果两组患者血液pH值比较,差异无统计学意义(P0.05)。观察组PaO_2高于对照组,PaCO_2低于对照组,差异均有统计学意义(P0.001)。观察组ICU住院时间、通气时间以及住院费用均低于对照组,差异有统计学意义(P0.001)。观察组呼吸机相关性肺炎发生率低于对照组,脱机成功率高于对照组,差异均有统计学意义(P0.05)。结论无创呼吸机在呼吸衰竭经鼻气管插管患者行有创机械通气可显著降低PaCO_2,提升PaO_2,同时呼吸机相关性肺炎发生率低,脱机率较高,更能降低住院时间及住院花费,具有可行性。
[Abstract]:Objective to investigate the feasibility of noninvasive mechanical ventilation in patients with respiratory failure by nasal endotracheal intubation. Methods 150 patients with respiratory failure who were treated in the first affiliated Hospital of Nanyang Medical College from September 2014 to September 2016 were treated with invasive mechanical ventilation through nasal tracheal intubation. 80 patients treated with non-invasive ventilator were divided into observation group and 70 patients who were not treated with non-invasive ventilator as control group. Blood pH value, arterial partial pressure of oxygen (Pao _ 2) and arterial blood carbon dioxide pressure (Paco _ 2) were monitored in the two groups, the hospitalization time, ventilation time and hospitalization cost in ICU were compared between the two groups, and the incidence of ventilator-associated pneumonia and the success rate of weaning were compared between the two groups. Results there was no significant difference in blood pH between the two groups (P 0.05). Pao _ 2 in observation group was significantly higher than that in control group (P 0.001). The ICU hospitalization time, ventilation time and hospitalization cost in the observation group were significantly lower than those in the control group (P 0.001). The incidence of ventilator-associated pneumonia in the observation group was lower than that in the control group, and the success rate of weaning was higher than that in the control group (P 0.05). Conclusion invasive mechanical ventilation in patients with respiratory failure through nasal endotracheal intubation can significantly reduce Paco _ 2 and increase PaO _ 2. At the same time, the incidence of ventilator-associated pneumonia is low, the weaning rate is higher, and it is feasible to reduce the hospitalization time and hospitalization cost.
【作者单位】：南阳医专第一附属医院;
【分类号】：R563.8

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