慢性阻塞性肺疾病患者肺部感染的临床特征及病原菌分布

发布时间：2018-07-04 21:47

本文选题：慢性阻塞性肺疾病 + 肺部感染　；参考：《中华医院感染学杂志》2017年14期

【摘要】：目的探讨慢性阻塞性肺疾病(COPD)伴肺部感染患者的临床特征及病原菌分布,为临床预防及治疗提供参考依据。方法选取2012年1月-2016年6月于医院呼吸内科收治的COPD患者642例,按是否感染分为肺部感染组310例和非肺部感染组332例;全面评估患者肺部感染情况,对患者进行相关病原学检查,对结果进行相关分析。结果肺部感染组患者在使用呼吸机、合并糖尿病、卧床方面分布率均高于非肺部感染组;肺部感染组患者在血红蛋白、血清白蛋白、用力肺活量(FVC1)、第1秒用力呼气容量(FEV_1)、FEV_1/FVC、动脉氧分压方面与非肺部感染组比较,差异均有统计学意义(P0.05);共送检肺部感染患者痰液标本310份,共检出251株病原菌,以革兰阴性菌为主,共158株占62.95%。结论 COPD患者肺部感染率较高,肺部感染病原菌以革兰阴性菌所占比重更大。
[Abstract]:Objective to investigate the clinical features and pathogenic bacteria distribution of chronic obstructive pulmonary disease (COPD) patients with pulmonary infection, and to provide reference for clinical prevention and treatment. Methods from January 2012 to June 2016, 642 COPD patients were divided into lung infection group (310 cases) and non-pulmonary infection group (332 cases) according to whether they were infected. The patients were examined for related etiology and the results were analyzed. Results the distribution rates of ventilator, diabetes mellitus and bed rest in pulmonary infection group were higher than those in non-pulmonary infection group, the hemoglobin and serum albumin in pulmonary infection group were higher than those in non-pulmonary infection group. Forced vital capacity (FVC1), FEV1 forced expiratory volume (FEV1), FEV1 / FVCand arterial oxygen partial pressure were significantly different from those of non-pulmonary infection group (P0.05), 310 sputum samples of pulmonary infection patients were examined, 251 strains of pathogenic bacteria were detected, mainly Gram-negative bacteria. 158 strains accounted for 62.95%. Conclusion the pulmonary infection rate was higher in COPD patients, and Gram-negative bacteria accounted for more of the pathogens of pulmonary infection.
【作者单位】：浙江省安吉县人民医院呼吸内科;
【分类号】：R563

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