乙醇性肝硬化患者肺部感染的危险因素分析

发布时间：2018-08-02 14:59

【摘要】：目的探讨分析引发乙醇性肝硬化患者肺部感染的危险因素以及预防与控制感染措施,以降低肺部感染率。方法选取2009年1月-2012年12月收治的110例乙醇性肝硬化患者为研究对象,将其中发生肺部感染的35例患者为感染组,余75例为未感染组,采用logistic回归分析法对乙醇性肝硬化患者肺部感染的相关因素进行统计分析。结果 110例乙醇性肝硬化患者中发生肺部感染35例,感染率为31.8%;35例感染患者中发热、外周血白细胞计数10×109/L、咳嗽、咳痰的阳性率分别为57.1%、51.4%、48.6%;共培养出病原菌19株,其中革兰阴性菌占68.4%,革兰阳性菌占21.1%,真菌占10.5%;肺部感染的发生与年龄、住院时间、肝衰竭、消化道出血、细菌性腹膜炎、肝性脑病及合并基础疾病有关(P0.05),与性别无明显相关性;采用非条件logistic回归分析法结果发现,年龄(OR=5.791,95%CI=1.704~19.681)、住院时间(OR=4.335,95%CI=1.341~14.017)、肝衰竭(OR=4.338,95%CI=1.012~19.198)、消化道出血(OR=6.909,95%CI=1.643~29.053)、细菌性腹膜炎(OR=5.593,95%CI=1.189~26.311)、肝性脑病(OR=3.939,95%CI=1.162~13.424)、合并基础性疾病(OR=5.259,95%CI=1.602~17.072)是乙醇性肝硬化患者住院期间肺部感染的主要危险因素(P0.05)。结论乙醇性肝硬化患者肺部感染率较高,医务人员要充分认识其危险因素,以预防和控制其发生。
[Abstract]:Objective to analyze the risk factors of pulmonary infection in patients with alcoholic cirrhosis and to prevent and control the infection in order to reduce the pulmonary infection rate. Methods from January 2009 to December 2012, 110 patients with ethanol-induced cirrhosis were selected as study subjects. 35 patients with pulmonary infection were selected as infection group and 75 patients as non-infected group. The correlation factors of pulmonary infection in patients with alcoholic cirrhosis were analyzed by logistic regression analysis. Results there were 35 cases of pulmonary infection in 110 patients with alcoholic cirrhosis, and the infection rate was 31.880%. The white blood cell count of peripheral blood was 10 脳 10 9 / L, the positive rates of cough and expectoration were 57.1% and 51.4% respectively, and 19 strains of pathogenic bacteria were cultured. The incidence of pulmonary infection was related to age, hospital stay, liver failure, gastrointestinal bleeding, bacterial peritonitis, hepatic encephalopathy and basic diseases (P0.05). The results of non-conditional logistic regression analysis showed that, 骞撮緞(OR=5.791,95%CI=1.704~19.681),浣忛櫌鏃堕棿(OR=4.335,95%CI=1.341~14.017),鑲濊“绔，

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