降钙素原与临床肺部感染评分评估呼吸机相关性肺炎预后的研究

发布时间：2019-05-24 07:02

【摘要】：目的研究探讨降钙素原与临床肺部感染评分在评估呼吸机相关性肺炎预后中的应用价值。方法将我院2014年8月至2015年8月接受机械通气治疗超过48 h的52例非呼吸机相关性肺炎与40例呼吸机相关性肺炎为本次研究活动的对象。在诊断的当天比较两组患者C-反应蛋白(CRP)、降钙素原(PCT)以及临床肺部感染评分(CPIS),且在诊断后1个月比较呼吸机相关性肺炎患者存活率个指标之间的差异。结果分析结果发现,呼吸机相关性肺炎患者的CRP、PCT以及CPIS均明显高于非呼吸机相关性肺炎,CRP诊断准确性相对较低,而联合应用PCT与CPIS可明显提高呼吸机相关性肺炎诊断率,数据符合统计学差异(P0.05);呼吸机相关性肺炎死亡患者中的PCT与CPIS高于存活患者,联合应用PCT与CPIS诊断特异度明显提高。结论临床诊断呼吸机相关性肺炎的时候,联合应用PCT与CPIS,可明显提高诊断的准确率与特异度,同时还可反映出患者病情进展状况,临床应用价值相对较高,可在临床上推广应用。
[Abstract]:Objective to investigate the value of procalcitonin and clinical pulmonary infection score in evaluating the prognosis of ventilator-associated pneumonia. Methods from August 2014 to August 2015, 52 cases of non-ventilator-associated pneumonia and 40 cases of ventilator-associated pneumonia were treated with mechanical ventilation for more than 48 hours. On the day of diagnosis, the C-reactive protein (CRP), procalcitonin (PCT) and clinical pulmonary infection score (CPIS), were compared between the two groups, and the survival rate of patients with ventilator-associated pneumonia was compared one month after diagnosis. Results the results showed that CRP,PCT and CPIS in patients with ventilator-associated pneumonia were significantly higher than those in patients with non-ventilator-associated pneumonia, and the diagnostic accuracy of CRP was relatively low. The combined application of PCT and CPIS could significantly improve the diagnostic rate of ventilator-associated pneumonia. The data were in accordance with the statistical difference (P 0.05). The diagnostic specificity of PCT and CPIS in patients with ventilator-associated pneumonia was significantly higher than that in patients with survival, and the specificity of combined PCT and CPIS was significantly higher than that in patients with ventilator-associated pneumonia. Conclusion in the clinical diagnosis of ventilator-associated pneumonia, the combined application of PCT and CPIS, can significantly improve the diagnostic accuracy and specificity, and can also reflect the progress of the patient, and the clinical application value is relatively high. It can be popularized and applied in clinic.
【作者单位】：赤峰学院附属医院;
【分类号】：R563.1

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