睡眠剥夺中感觉运动皮层和视觉皮层神经活动及警觉水平的改变（英文）
发布时间：2023-01-14 15:38
在睡眠剥夺（sleep deprivation,SD）过程中,人类大脑的神经活动和警觉水平如何受到影响,尤其是感觉运动和视觉系统,目前仍是研究的热点.静息状态功能磁共振成像（resting state functional magnetic resonance imaging,rf MRI）作为一种反映人脑自发活动的非侵入式成像技术,在睡眠剥夺的研究中得到了广泛应用.本研究采用9次重复rf MRI和心理运动警觉任务（psychomotor vigilance task,PVT）,以探索23名志愿者在整个36 h的睡眠剥夺过程中神经活动和警觉水平的变化.采用基于PVT的平均反应时间（mean reaction time,MRT）和失效率（lapses ratio,LR）评估警觉水平的变化;采用基于rf MRI的区域同质性（region homogeneity,Re Ho）和低频波动幅度（amplitude of low frequency fluctuation,ALFF）评估大脑神经活动变化.结果表明,感觉运动网络（sensorimotor network,SMN）和视觉区域（visu...
【文章页数】：18 页
【文章目录】：
1 Materials and methods
1.1 Subjects and materials
1.2 MRI data acquisition
1.3 Data preprocessing
1.4 Calculation of ReHo and ALFF
1.5 Definitions of visual-related regions and sensorimotor-related regions
1.6 Statistical analysis
2 Results
2.1 Effect of SD on vigilance level
2.2 Effect of SD on ReHo
2.3 Effect of SD on ALFF
2.4 Brain regions with both ReHo and ALFF affected
2.5 Pattern of alteration of neural activities in SMN and VN regions
2.6 Effects of sleep pressure,circadian rhythm and their interaction
2.7 Results of correlation analysis
3 Discussion
4 Conclusion
本文编号：3730694
【文章页数】：18 页
【文章目录】：
1 Materials and methods
1.1 Subjects and materials
1.2 MRI data acquisition
1.3 Data preprocessing
1.4 Calculation of ReHo and ALFF
1.5 Definitions of visual-related regions and sensorimotor-related regions
1.6 Statistical analysis
2 Results
2.1 Effect of SD on vigilance level
2.2 Effect of SD on ReHo
2.3 Effect of SD on ALFF
2.4 Brain regions with both ReHo and ALFF affected
2.5 Pattern of alteration of neural activities in SMN and VN regions
2.6 Effects of sleep pressure,circadian rhythm and their interaction
2.7 Results of correlation analysis
3 Discussion
4 Conclusion
本文编号：3730694
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