脑外伤后颅内感染患者血液流变学指标的变化观察

发布时间：2018-01-30 11:53

本文关键词： 脑外伤颅内感染血液流变学指标　出处：《中华医院感染学杂志》2017年05期 　论文类型：期刊论文

【摘要】：目的观察脑外伤后患者颅内感染血液流变学指标的变化情况,为脑外伤后颅内感染的治疗提供依据。方法选取2013年7月-2015年8月医院收治的脑外伤后颅内感染患者43例为观察组,并以同时期的脑外伤后未发生颅内感染的患者43例为对照组,然后将两组患者的高切、中切及低切全血黏度、全血还原黏度及其他血流变指标进行比较,并比较轻度、中度及重度颅内感染者的上述检测结果。结果观察组高切、中切及低切全血黏度分别为(5.33±0.45)mPa·s、(6.28±0.62)mPa·s及(12.83±1.37)mPa·s,均高于对照组(4.20±0.33)mPa·s、(5.11±0.50)mPa·s及(8.98±1.13)mPa·s;观察组高切、中切及低切全血还原黏度及血沉方程K值、红细胞聚集指数、血细胞比容(%)为(8.72±0.75)mPa·s、(11.90±1.25)mPa·s、(24.54±2.20)mPa·s、103.63±10.67、16.48±3.23、(45.35±3.78)%,均明显高于对照组(6.16±0.59)mPa·s、(8.86±0.88)mPa·s、(17.67±1.55)mPa·s、88.35±7.27、11.35±2.25、(39.89±3.32)%;同时,中度感染、重度感染患者全血黏度(高切、中切、低切)、全血还原黏度(高切、中切、低切)、血沉方程K值、红细胞聚集指数、血细胞比容(%),均高于轻度感染,且重度感染患者相关指标均高于中度感染,差异均有统计学意义(P0.05)。结论脑外伤后颅内感染患者血液流变学指标的变化较为明显,且颅内感染严重程度对其检测水平影响较大。
[Abstract]:Objective to observe the changes of hemorheology in patients with intracranial infection after traumatic brain injury. Methods from July 2013 to August 2015, 43 patients with intracranial infection after traumatic brain injury were selected as the observation group. 43 patients without intracranial infection in the same period of brain trauma were taken as control group. The high, middle and low shear whole blood viscosity, whole blood reduction viscosity and other hemorheological indexes were compared between the two groups. Results the whole blood viscosity of the observation group was 5.33 卤0.45mPa 路s, which was higher than that of the control group. 6.28 卤0.62mPa 路s and 12.83 卤1.37mPa 路s were higher than those of the control group (4.20 卤0.33mPa 路s). 5.11 卤0.50mPa 路s and 8.98 卤1.13mPa 路s; In the observation group, the viscosity of whole blood reduction, erythrocyte aggregation index, erythrocyte aggregation index and hematocrit were 8.72 卤0.75 mPa 路s. 11.90 卤1.25mPa 路scai 24.54 卤2.20mPa 路sch 103.63 卤10.67c16.48 卤3.23. 45.35 卤3.78 mPa 路s was significantly higher than that in the control group (6.16 卤0.59mPa 路scai 8.86 卤0.88mPa 路s). 17.67 卤1.55mPa 路sch 88.35 卤7.27mPa. 11.35 卤2.25mPa. 39.89 卤3.32m; At the same time, the whole blood viscosity (high shear, middle cut, low cut, whole blood reduction viscosity (high shear, middle cut, low cut, ESR equation K value, erythrocyte aggregation index, hematocrit) in patients with moderate infection and severe infection). All of them were higher than mild infection, and the related indexes of patients with severe infection were higher than those of moderate infection. Conclusion the changes of hemorheology in patients with intracranial infection after brain injury are obvious, and the severity of intracranial infection has a great influence on the detection level.
【作者单位】：南阳市第二人民医院护理部;南阳市第二人民医院医务部;南阳市第二人民医院神经外科;南阳市第二人民医院神经外科ICU;
【基金】：河南省医学科技攻关计划指导性计划基金资助项目(201312023)
【分类号】：R651.15
【正文快照】： 颅脑损伤是临床常见危重症疾病之一,其发病与交通事故、跌倒、高处坠落、工伤事故等有关,临床表现为意识障碍、呕吐、头痛、昏迷等,危及生命安全。颅脑外伤具有发病率高、病死率高的特点[1]。由于脑外伤病情危重,早期易感染。有调查研究显示[2],神经外科重症监护病房院内感染

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