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中重度颅脑损伤后Rotterdam CT评分、颅内压及预后三者之间相关性的研究

发布时间:2018-02-02 10:21

  本文关键词: 颅脑损伤 CT 颅内压 GOS评分 出处:《大连医科大学》2013年硕士论文 论文类型:学位论文


【摘要】:目的:研究中重度颅脑损伤患者颅内压与CT影像特点的关系,进一步结合Rotterdam CT评分分析它们与预后情况的相关性,为正确治疗及早期评估预后情况提供新的思路。 方法:对28名伤后24h内入院的中重度颅脑损伤患者行颅内压监测和头部CT扫描,每15分钟记录颅内压值,记录CT扫描后基底池受压、中线移位、脑室受压的情况,并进行Rotterdam CT评分,分析CT评分,颅内压,,预后三者之间的关系。 结果:1.CT影像中基底池受压、中线移位、脑室受压程度、Rotterdam CT评分不同时,中重度颅脑损伤患者的颅内压水平也不同。基底池开放、部分闭塞和完全闭塞时,ICPCT分别为18.92±1.89mm Hg、23.87±3.90mm Hg、32.56±3.99mmHg;中线移位≤5mm与中线移位5mm时,ICPCT分别为23.96±6.12mm Hg、32.32±3.75mm Hg;脑室颅腔比值≤0.2与脑室颅腔比值0.2时,ICPCT分别为30.24±5.04mm Hg、23.66±5.64mmHg;Rotterdam CT评分分别为3分、4分、5分时,ICPCT分别为20.95±2.48mm Hg、28.16±4.42mm Hg、33.05±2.84mm Hg。采用Mann-Whitney U检验各组之间存在统计学差异(P≤0.05)。使用Spearman等级相关分析基底池情况、中线移位、脑室体积、Rotterdam CT评分与颅内压的相关性分别为:rho=-0.821、rho=0.472、rho=-0.548、rho=0.890,其中Rotterdam CT评分与颅内压水平的相关性最强。2.中重度颅脑损伤患者预后良好组与预后不良组比较:基底池情况得分分别为1.94±0.64、2.50±0.71;Rotterdam CT评分分别为3.33±0.84、4.50±1.08。两组之间比较有统计学意义(P≤0.05);但是这两组CT影像中线移位分别为3.58±2.33mm、6.25±3.78mm;脑室体积分别为0.263±0.06、0.224±0.08。采用Mann-Whitney U检验分析,P0.05,两组之间无统计学差异。3. Rotterdam CT评分和伤后24小时颅内压水平与预后相关性分别为rho=-0.625、rho-0.763。伤后24小时颅内压水平与预后相关性最强,其次是Rotterdam CT评分,基底池情况,入院GCS评分,而中线移位和脑室受压情况与预后无明显相关性。 结论:1.颅脑损伤后CT影像特点包括基底池情况、中线移位、脑室受压情况与颅内压存在相关性,但Rotterdam CT评分与颅内压的相关性更精准,颅脑损伤后可以根据这些CT特征及Rotterdam CT评分初步评估颅内压情况,为进一步治疗提供思路。2.采用单个的CT影像特征预测预后存在一定的局限性,而综合了大部分CT影像特点的Rotterdam CT评分则是较好的选择。颅脑损伤后颅内压与预后情况存在很强相关性,对于中重度颅脑损伤患者行颅内压监测并根据监测情况进行相关治疗将有利于预后。
[Abstract]:Objective: to study the relationship between intracranial pressure and CT imaging features in patients with moderate and severe craniocerebral injury, and to analyze the correlation between intracranial pressure and prognosis combined with Rotterdam CT score. To provide a new idea for correct treatment and early evaluation of prognosis. Methods: Intracranial pressure monitoring and head CT scan were performed in 28 patients with moderate and severe craniocerebral injury within 24 hours after injury. Intracranial pressure was recorded every 15 minutes. The relationship among CT score, intracranial pressure and prognosis was analyzed. Results 1. In CT images, the basal cistern was compressed, the midline shifted, and the degree of ventricular compression was not the same as Rotterdam CT score. ICPCT was 18.92 卤1.89 mm Hg in patients with moderate and severe craniocerebral injury. 23.87 卤3.90 mm HgN 32.56 卤3.99 mm Hg; When the midline displacement 鈮

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