持续气道正压通气对非急性期脑梗死合并阻塞性睡眠呼吸暂停综合征患者炎症因子的影响

发布时间：2018-02-09 19:49

本文关键词： 持续气道正压通气脑梗死阻塞性睡眠呼吸暂停综合征 C反应蛋白白细胞介素- 白细胞介素-　出处：《中国老年学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的观察持续气道正压通气(CPAP)治疗后非急性期脑梗死合并阻塞性睡眠呼吸暂停综合征(OSAHS)患者体内炎症因子的变化。方法 86例非急性期脑梗死合并OSAHS患者,随机分为实验组及对照组。对照组给予常规脑梗死控制治疗。实验组在常规脑梗死治疗基础给予CPAP治疗,历时半年。分别于治疗前、治疗后1、3、6个月检测C反应蛋白(CRP)、白细胞介素(IL)-1、IL-6水平。结果两组不同时段CRP、IL-1、IL-6水平均有显著差异(P0.05)。结论 CPAP治疗可以控制非急性期脑梗死合并OSAHS患者炎症反应。
[Abstract]:Objective to observe the changes of inflammatory factors in patients with non-acute cerebral infarction complicated with obstructive sleep apnea syndrome (OSAHS) after continuous positive airway pressure ventilation (CPAP). The experimental group was divided into experimental group and control group randomly. The control group was given conventional cerebral infarction control therapy. The experimental group was treated with CPAP on the basis of routine cerebral infarction treatment for half a year. The levels of C-reactive protein (CRP) and interleukin-1 (IL-1) IL-6 were measured at 3 and 6 months after treatment. Results there were significant differences in the levels of IL 6 between the two groups at different time points. Conclusion CPAP treatment can control the inflammatory response of patients with OSAHS in non-acute cerebral infarction.
【作者单位】：广东医科大学附属第二医院呼吸内科;
【基金】：湛江市财政资金科技专项竞争性分配项目(No.2013A01017)
【分类号】：R766;R743.33

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