某院烧伤患者创面病原菌耐药性调查分析

发布时间：2018-02-09 22:35

本文关键词： 烧伤病原菌耐药性　出处：《重庆医学》2016年17期 　论文类型：期刊论文

【摘要】：目的了解该院烧伤患者感染病原菌标本来源、分布及耐药情况。方法收集该院2011年7月至2014年6月全军烧伤中心送检的3 595份标本的来源、分布和药敏结果进行回顾性分析。结果在送检标本中烧伤创面分泌物占69.49%,阳性率达到了81.51%;血液占19.55%,阳性率达到了23.90%;共检出2 445株病原菌,其中革兰阴性菌(G-)占58.2%,革兰阳性菌(G+)占38.69%,真菌9种76株,占3.11%,其中耐甲氧西林金黄色葡萄球菌(MRSA)的为最高,占总病原菌的22.66%;药物敏感试验显示,各检出菌有多药耐药性;G+对万古霉素敏感,G-对头孢哌酮舒巴坦敏感。结论烧伤科细菌感染以G-为主,对碳青霉烯类敏感率有下降的趋势,在检出率方面MRSA有增多的趋势,临床应重视根据药敏试验用药,以延缓细菌耐药率。
[Abstract]:Objective to investigate the origin, distribution and drug resistance of pathogenic bacteria from burn patients in our hospital. Methods from July 2011 to June 2014, 3 595 specimens were collected from burn center of the whole army. The results of distribution and drug sensitivity were analyzed retrospectively. Results the positive rate of burn wound secretion was 69.49, the positive rate was 81.51, the blood accounted for 19.55m, the positive rate was 23.900.A total of 2,445 strains of pathogenic bacteria were detected. Gram-negative bacteria (G-G) accounted for 58.2%, Gram-positive bacteria (G) accounted for 38.69, fungi of 9 species (76 strains) accounted for 3.11.The methicillin-resistant staphylococcus aureus (MRSA) was the highest, accounting for 22.66% of the total pathogenic bacteria. The multidrug resistance of G was sensitive to vancomycin and G- was sensitive to cefoperazone sulbactam. Conclusion the infection rate of bacteria in Burns is mainly G-, and the sensitivity to carbapenes is decreasing, and the detection rate of MRSA is increasing. Clinical attention should be paid to drug use according to drug sensitivity test in order to delay the rate of drug resistance of bacteria.
【作者单位】：中国人民解放军第159中心医院药械科;
【分类号】：R644;R446.5

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